Results 181 to 190 of about 49,025 (266)

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

A robust deep learning approach for impulse noise filtering using hybrid auto-encoder with fuzzy median filter. [PDF]

PLoS One
Naeem M, Bhatti SM, Rashid M, Jaffar A, Akram S, Fida B, Ahmad A.   +6 more
europepmc   +1 more source

Prior Expectations Bias Confidence Judgments Through Parietal Alpha‐Band Modulation

Advanced Science, EarlyView.
ABSTRACT Humans possess the metacognitive ability to estimate the likely accuracy of their own decisions through confidence judgments. Yet, whether prior information shapes confidence and the neural mechanisms mediating such influence, remain to be determined.
Luca Tarasi, Anna Pasini, Domenico Romanazzi, Margherita Covelli, Vincenzo Romei   +4 more
wiley   +1 more source

Causal Structure Learning Assumptions Shape Counterfactual Safety: Expert-Guided Constraints vs. Data-Driven DAGs with Probabilistic Logic Twin Networks. [PDF]

Entropy (Basel)
Avilés H, Gracia I, Kiesel R, Rodríguez V, Machucho R, Reyes A, Negrete M, Ramírez G, Luévano N, Pequeño M, Medrano J, Weitkämper F.   +11 more
europepmc   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

A logic-based knowledge-driven bidirectional multi-attention GRU framework for fear level classification in humans. [PDF]

Sci Rep
Joshva AA, Balasubramanian VK, Murugappan M.   +2 more
europepmc   +1 more source

An On‐Demand Neuromorphic Vision System Enabled by a Multi‐Paradigm Neuromorphic Device and Hierarchical Reconfigurability Designed from Device to System Level

Advanced Science, EarlyView.
An on‐demand ultra‐reconfigurable intelligent vision system with hierarchical reconfigurability from device to system levels is demonstrated. Through co‐design of a multi‐paradigm device, reconfigurable circuits, and adaptive system architecture/algorithms, the system enables seamless switching among spiking, non‐spiking, neuromorphic imaging (NI), and
Biyi Jiang, Jiayi Xu, Liang Ran, Xinhe Feng, Khalil Harrabi, Yida Li, Longyang Lin, Feichi Zhou   +7 more
wiley   +1 more source

IoT-Simulated Digital Twin with AI Traffic Signal Control for Real-Time Traffic Optimization in SUMO. [PDF]

Sensors (Basel)
Ceapă VCD, Apostol VA, Sacală IS, Căruntu CF, Ross R, Holt D, Segărceanu M, Burlacu LE.   +7 more
europepmc   +1 more source

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

Artificial intelligence assisted simulation and surgical video analytics for ophthalmic surgery training and competence development. [PDF]

Front Med (Lausanne)
Zhao M, Li J, Li S, Liu J, Jiang Y, Lai X, Yang J, Pang L, Tang L, Li K, Jiang L.   +10 more
europepmc   +1 more source