Results 131 to 140 of about 857,290 (286)

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

Logical segmentation for article extraction in digitized old newspapers

open access: yes, 2012
Newspapers are documents made of news item and informative articles. They are not meant to be red iteratively: the reader can pick his items in any order he fancies.
Hébert, David   +4 more
core   +1 more source

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

open access: yesAdvanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang   +15 more
wiley   +1 more source

Wittgenstein's True Thoughts

open access: yesNordic Wittgenstein Review, 2013
The central remarks of the Tractatus are without substantial content or consequence, remarks at the boundaries of sense that dissolve into truth.  While they say nothing, they encapsulate logical features of the language and the world.
Andrew Lugg
doaj  

An Integrated NLP‐ML Framework for Property Prediction and Design of Steels

open access: yesAdvanced Science, EarlyView.
This study presents a data‐driven framework that uses language‐processing techniques to interpret steel processing descriptions and machine‐learning models to predict mechanical properties. By organising complex process histories into meaningful groups and enabling rapid property forecasts, the work supports faster, more informed steel design through ...
Kiran Devraju   +5 more
wiley   +1 more source

Random Time‐Space Coding Metasurfaces for Spatial Control of the Temporal Statistics of Electromagnetic Fields

open access: yesAdvanced Science, EarlyView.
A probabilistic framework based on random time‐space coding metasurfaces enables control of the spatial distribution of electromagnetic fields temporal statistics. By tailoring the marginal and joint distributions of random codes, electromagnetic fields with desired mean and variance patterns are realized, enabling simultaneous transmission and jamming.
Jia Cheng Li   +3 more
wiley   +1 more source

Study of Free‐Space Optical Quantum Network: Review and Prospectives

open access: yesAdvanced Science, EarlyView.
Free from the constraints of fiber connections, free‐space quantum network enables longer and more flexible quantum network connections. This review summarizes and comparatively analyzes free‐space quantum network experiments based on ground stations, satellites, and mobile platforms.
Hua‐Ying Liu, Zhenda Xie, Shining Zhu
wiley   +1 more source

AGRICULTURAL INDUSTRIALIZATION AND SUSTAINABLE DEVELOPMENT: A GLOBAL PERSPECTIVE [PDF]

open access: yes
Agricultural industrialization and sustainable development issues are important contemporary areas of debate. This paper argues that the two processes are a consequence of a set of forces operating in our global system. It outlines a number of conceptual
Davis, Carlton George, Langham, Max R.
core   +1 more source

Organic Crystal‐MXene Composites as Temperature‐Tolerant Strain Sensors

open access: yesAdvanced Science, EarlyView.
ABSTRACT Flexible organic crystals offer significant opportunities for organic electronics; however, their potential applications in fields like flexible sensors are at present limited by poor charge transport that result in failure under reversible conditions.
Xuesong Yang   +10 more
wiley   +1 more source

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