Results 181 to 190 of about 977,806 (290)

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao   +5 more
wiley   +1 more source

Ion‐Lock Storage With Multi‐Logic Circuitry Gated by Polar–Dipolar Interactions in Poly(Ionic Liquids)

open access: yesAngewandte Chemie, EarlyView.
Precise building block design of poly(ionic liquids) creates an opportunity to achieve ionic conductivity, energy storage, and multi‐value logic in one material while eliminating elaborate fabrication processes. ABSTRACT In these studies, we developed a new generation of polymeric materials capable of electrical energy storage and forming higher‐than ...
Sourav Biswas   +3 more
wiley   +2 more sources

Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs

open access: yesAdvanced NanoBiomed Research, EarlyView.
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna   +9 more
wiley   +1 more source

Advances in Regulating Strategies and Applications of Ferroelectric Materials

open access: yesAdvanced Physics Research, EarlyView.
To meet the demand for precise control of performance in nanoelectronic devices, this paper systematically reviews the latest advances in controlling ferroelectric properties through strategies such as external field modulation, low‐dimensional confinement, interface engineering, and topological structure design.
Jianying Ji, Cong Liu, Dan Luo, Zhou Li
wiley   +1 more source

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