Results 31 to 40 of about 2,808 (225)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
El Evangelio de Tomás y algunos aspectos de la cuestión sinóptica
Estudios Eclesiásticos, 1960 El Evangelio apócrifo de Tomás aporta nuevos logion de Jesús, dos parábolas y ocho dichos aislados. Se busca, en la medida de lo posible, acercarse al menos a la veracidad de dichas aportaciones de Tomás.
Salvador Muñoz Iglesias
doaj
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Niektóre aspekty trynitologii współczesnej
Analecta CracoviensiaW ostatnim okresie można zauważyć w teologii odnowione zainteresowanie pierwszą tajemnicą wiary chrześcijańskiej, którą jest tajemnica Trójcy Świętej. Efekty refleksji teologicznej w tej dziedzinie są coraz bardziej widoczne.
Janusz Królikowski
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Did Jesus Exclude Women from Priesthood? [PDF]
, 1977 This sentence purports to give the principle upon which the fundamental affirmation of the Declaration rests, namely, the Sacred Congregation for the Doctrine of the Faith judges it necessary to recall that the Church , in fidelity to the example of the
Schneiders, Sandra Marie
core +1 more source
The Non-Cyprianic Scripture Texts in Lactantius' Divine Institutes [PDF]
, 1982 The state of the textual tradition regarding the Lactantian citations of scripture is in need of radical ...
McGuckin, John A.
core +2 more sources