Results 41 to 50 of about 531 (230)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The Temple in the Gospel of Thomas. An Interpretive Perspective on Some Words Attributed to Jesus
, 2017 The essay investigates the conception of "Temple" in the Gospel of Thomas, starting from the analysis of logion 71, which is a parallel of the Jesus' sayings about destruction/rebuilding of the Jerusalem Temple, attested in the Synoptics, the Gospel of ...
Andrea Annese, Annese, Andrea
core +1 more source
TheoRhēma, 2014 The current piece of research has evidenced that the concept of the Kingdom of God / Kingdom of Heaven is not new in the biblical theology of the human writers of the Scripture.
Gallusz László
doaj
Philo-L1: The Emendatio of Latin Texts as a Denoising Problem
Umanistica DigitaleThe emendation of ancient literary texts is one of the most challenging tasks in classical philology. Existing models designed to assist with this task (Latin BERT and Logion) rely on a fill-mask approach that presents significant limitations. This paper
Giuseppe Ferrara
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Niektóre aspekty trynitologii współczesnej
Analecta CracoviensiaW ostatnim okresie można zauważyć w teologii odnowione zainteresowanie pierwszą tajemnicą wiary chrześcijańskiej, którą jest tajemnica Trójcy Świętej. Efekty refleksji teologicznej w tej dziedzinie są coraz bardziej widoczne.
Janusz Królikowski
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
, 2017 The logion of Matt 11.27 (// Luke 10.22) – ‘All things have been handed over to me by my Father; and no one knows the Son except the Father, and no one knows the Father except the Son and anyone to whom the Son chooses to reveal him’ – has long been ...
Marc Rastoin
core +1 more source