Results 31 to 40 of about 2,838 (236)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

El Evangelio de Tomás y algunos aspectos de la cuestión sinóptica

open access: yesEstudios Eclesiásticos, 1960
El Evangelio apócrifo de Tomás aporta nuevos logion de Jesús, dos parábolas y ocho dichos aislados. Se busca, en la medida de lo posible, acercarse al menos a la veracidad de dichas aportaciones de Tomás.
Salvador Muñoz Iglesias
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Benedict XVI and the Foundations of Politics

open access: yesWrocławski Przegląd Teologiczny
This article aims to present the political theology of Joseph Ratzinger/Benedict XVI. The first paragraph focuses on Ratzinger’s interpretation of selected New Testament source texts and the basic assumptions of what he called the “service to politics ...
Henryk Seweryniak
doaj   +1 more source

El Stromata VIII de Clemente de Alejandría [PDF]

open access: yes, 2005
SUMARIO: 1. EL ESTADO DE LA CUESTION. 2. LA INVESTIGACION SOBRE LA AUTORfA Y COMPOSICION DEL TEXTO. 3. Los OBjETivos PROGRAMATICOS DE CLEMENTE. 4. Los cuATRO CLTIMOS CAPITULOS DE STROMATA V I L 5. EL LIBRO VIII DE LOS STROMATA. A.
Merino, M. (Marcelo)
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Niektóre aspekty trynitologii współczesnej

open access: yesAnalecta Cracoviensia
W ostatnim okresie można zauważyć w teologii odnowione zainteresowanie pierwszą tajemnicą wiary chrześcijańskiej, którą jest tajemnica Trójcy Świętej. Efekty refleksji teologicznej w tej dziedzinie są coraz bardziej widoczne.
Janusz Królikowski
doaj   +1 more source

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