Results 161 to 170 of about 1,559,766 (320)

Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8+ T Cells Apoptosis with Calcium Overload and Mitochondrial Dysfunction

Advanced Science, EarlyView.
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu, Peng Peng, Changze Wei, Fanhui Meng, Xiaoyao Huang, Peisheng Liu, Siyuan Fan, Xinyue Cai, Meiling Wu, Zilin Xuan, Qing Liu, Xinyu Qiu, Zhenlai Zhu, Hao Guo   +13 more
wiley   +1 more source

Machine Learning‐Based Radiomics in Malignancy Prediction of Pancreatic Cystic Lesions: Evidence from Cyst Fluid Multi‐Omics

Advanced Science, EarlyView.
This study develops noninvasive clinical‐radiomic models using preoperative CT images to predict the malignant potential of pancreatic cystic lesions. It demonstrates the models' high accuracy across various datasets, with AUCs exceeding 0.92. Additionally, multi‐omics analyses uncover key biological mechanisms, including secretion function and lipid ...
Sihang Cheng, Ge Hu, Shenbo Zhang, Rui Lv, Limeng Sun, Zhe Zhang, Zhengyu Jin, Yanyan Wu, Chen Huang, Lu Ye, Zhe‐Sheng Chen, Yunlu Feng, Aiming Yang, Zhiwei Wang, Huadan Xue   +14 more
wiley   +1 more source

A logistic regression model when some events precede treatment: The effect of thrombolytic therapy for acute myocardial infarction on the risk of cardiac arrest

, 1997
Christopher H. Schmid, Ralph B. D’Agostino, John L. Griffith, Joni R. Beshansky, Harry P. Selker   +4 more
openalex   +1 more source

Correlation Between Fecal Microbiota and Corticosteroid Responsiveness in Primary Immune Thrombocytopenia: an Exploratory Study

Advanced Science, EarlyView.
This study uses gut microbiome data to predict corticosteroid response in patients with immune thrombocytopenia (ITP). Fecal samples from 212 patients with ITP are sequenced. Six machine‐learning algorithms are used to train predictive models. The support vector machine‐based model integrated clinical data and selected microbial species, diversities ...
Feng‐Qi Liu, Zhuo‐Yu An, Li‐Juan Cui, Meng‐Yu Xiao, Ye‐Jun Wu, Wei Li, Bang‐Shuo Zhang, Li Yu, Jia Feng, Zhuo‐Gang Liu, Ru Feng, Zhong‐Xing Jiang, Rui‐Bin Huang, Hong‐Mei Jing, Jin‐Hai Ren, Xiao‐Yu Zhu, Yun‐Feng Cheng, Yu‐Hua Li, He‐Bing Zhou, Da Gao, Yi Liu, Fan Yu, Xin Wang, Jian‐Lin Qiao, Dai‐Hong Hu, Lu‐Lu Wang, Meng‐Tong Zang, Qi Chen, Qing‐Yuan Qu, Jian‐Ying Zhou, Meng‐Lin Li, Yu‐Xiu Chen, Qiu‐Sha Huang, Hai‐Xia Fu, Yue‐Ying Li, Qian‐Fei Wang, Xiao‐Jun Huang, Xiao‐hui Zhang, the Cooperative ITP Working Group   +38 more
wiley   +1 more source

Finite-sample performance of the maximum likelihood estimator in logistic regression [PDF]

arXiv
Logistic regression is a classical model for describing the probabilistic dependence of binary responses to multivariate covariates. We consider the predictive performance of the maximum likelihood estimator (MLE) for logistic regression, assessed in terms of logistic risk.
arxiv  

Predictors of psychiatric disorders in liver transplantation candidates: Logistic regression models [PDF]

, 2003
Paola Rocca, Elena Cocuzza, Roberta Rasetti, Giuseppe Rocca, Enrico Zanalda, Filippo Bogetto   +5 more
openalex   +1 more source

CircRNA‐mTOR Promotes Hepatocellular Carcinoma Progression and Lenvatinib Resistance Through the PSIP1/c‐Myc Axis

Advanced Science, EarlyView.
This study verifies that circRNA‐mTOR exhibits high expression levels in HCC and has a strong correlation with patient prognosis. Mechanistically, circRNA‐mTOR achieves this effect by facilitating the nuclear translocation of RNA‐binding protein (RBP) PSIP1 through specific binding.
Yongchang Tang, Feng Yuan, Mingbo Cao, Yupeng Ren, Yuxuan Li, Gaoyuan Yang, Zhaozhong Zhong, Hao Liang, Zhiyong Xiong, Zhiwei He, Nan Lin, Meihai Deng, Zhicheng Yao   +12 more
wiley   +1 more source

A Note on the Presence of Spurious Pseudo-Guessing Parameters for Three-Parameter Logistic Models in Heterogeneous Populations. [PDF]

Educ Psychol Meas, 2020
Raykov T, Marcoulides GA.
europepmc   +1 more source

Saturated logistic avalanche model [PDF]

, 2003
G. Aielli, P. Camarri, R. Cardarelli, A. Di Ciaccio, B. Liberti, A. Paoloni, R. Santonico   +6 more
openalex   +1 more source

HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou, Yan Guo, Shuang Xu, Mi Bai, Weidong Cao, Yue Zhang, Zhanjun Jia, Aihua Zhang   +7 more
wiley   +1 more source