Results 61 to 70 of about 25,855,092 (323)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

MRI feature-based discrimination model for prediction of MGMT promoter methylation status in glioma

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To explore the potential value of expert-identified CT and MRI imaging features in predicting the MGMT promoter methylation status in glioma. Methods A retrospective analysis was conducted in 188 patients in The First Medical Center of Chinese
ZHANG Zhi-zhong, YOU Na, LIU Ming-hang, LI Ze, SUN Guo-chen, ZHAO Kai   +5 more
doaj   +1 more source

Developing prediction models for clinical use using logistic regression: an overview.

Journal of Thoracic Disease, 2019
Prediction models help healthcare professionals and patients make clinical decisions. The goal of an accurate prediction model is to provide patient risk stratification to support tailored clinical decision-making with the hope of improving patient ...
M. Shipe, S. Deppen, F. Farjah, E. Grogan   +3 more
semanticscholar   +1 more source

Soft Computing Ensemble Models Based on Logistic Regression for Groundwater Potential Mapping

Applied Sciences, 2020
Groundwater potential maps are one of the most important tools for the management of groundwater storage resources. In this study, we proposed four ensemble soft computing models based on logistic regression (LR) combined with the dagging (DLR), bagging (
Phong T. Nguyen, Duong Hai Ha, Mohammadtaghi Avand, A. Jaafari, H. Nguyen, N. Al‐Ansari, Tran Van Phong, Rohit Sharma, Raghvendra Kumar, H. V. Le, Lanh Si Ho, Indra Prakash, B. Pham   +12 more
semanticscholar   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Analysis of factors influencing the severity of acute phase and short - term prognosis of anti-N-methyl-D-aspartate receptor encephalitis

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To explore the factors influencing the severity of acute phase and short-term prognosis of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis, and search for potential indicators for assessing disease severity and predicting prognosis ...
YE Rui-xi, CAI Lin-jun, KONG Xue-ying, LI Jin-mei, ZHOU Dong, HONG Zhen   +5 more
doaj   +1 more source

Gompertz and Logistic Models to the Productive Traits of Sunn Hemp

, 2017
Studies on growth models for productive character of sunn hemp are important to know the behavior of the culture. Therefore, the objective of this research was to adjust non-linear models, Gompertz and Logistic, in the description of productive traits of
C. Bem, A. C. Filho, Gabriela Görgen Chaves, J. A. Kleinpaul, R. Pezzini, A. Lavezo   +5 more
semanticscholar   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Estimation of the growth curve parameters in Macrobrachium rosenbergii [PDF]

, 2011
Growth is one of the most important characteristics of cultured species. The objective of this study was to determine the fitness of linear, log linear, polynomial, exponential and Logistic functions to the growth curves of Macrobrachium rosenbergii ...
Gopal, Krishna, Nagulu, Banoth, Satyanarayana, Y., Srinivasa Rao, P.   +3 more
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