Results 41 to 50 of about 1,754,722 (270)

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Logistic regression analysis with standardized markers

The Annals of Applied Statistics, 2013
Two different approaches to analysis of data from diagnostic biomarker studies are commonly employed. Logistic regression is used to fit models for probability of disease given marker values, while ROC curves and risk distributions are used to evaluate classification performance.
Huang, Ying, Pepe, Margaret S., Feng, Ziding   +2 more
openaire   +4 more sources

An Answer to Multiple Problems with Analysis of Data on Harms?

, 2012
Discussion of "Multivariate Bayesian Logistic Regression for Analysis of Clinical Trial Safety Issues" by W. DuMouchel [arXiv:1210.0385].Comment: Published in at http://dx.doi.org/10.1214/12-STS381C the Statistical Science (http://www.imstat.org/sts ...
Evans, Stephen
core   +1 more source

Neural Networks in Bankruptcy Prediction - A Comparative Study on the Basis of the First Hungarian Bankruptcy Model [PDF]

, 2005
The article attempts to answer the question whether or not the latest bankruptcy prediction techniques are more reliable than traditional mathematical–statistical ones in Hungary.
Kristóf, Tamás, Virág, Miklós
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Word2Vec on Sentiment Analysis with Synthetic Minority Oversampling Technique and Boosting Algorithm

Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi), 2022
Customer opinion is an important aspect in determining the success of a company or service provider. By determining the sentiment of the existing opinion, the company can use it as an evaluation material to improve the quality of the service or product ...
Rayhan Rahmanda, Erwin Budi Setiawan
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Applying the Binary Logistic Regression Analysis on The Medical Data

Science Journal of University of Zakho, 2017
In this paper, the Binary Logistic Regression Analysis BLRA technique has been used and applied for building the best model for Hepatitis disease data using best subsets regression and stepwise procedures and depending on some laboratory tests such as ...
Qais M. Abdulqader
doaj   +1 more source

Noncollapsibility and its role in quantifying confounding bias in logistic regression

BMC Medical Research Methodology, 2021
Background Confounding bias is a common concern in epidemiological research. Its presence is often determined by comparing exposure effects between univariable- and multivariable regression models, using an arbitrary threshold of a 10% difference to ...
Noah A. Schuster, Jos W. R. Twisk, Gerben ter Riet, Martijn W. Heymans, Judith J. M. Rijnhart   +4 more
doaj   +1 more source