Results 71 to 80 of about 448,016 (347)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Measurement of Logistics Radiation Range and Improvement of Logistics Radiation Ability of City Clusters

open access: yesDiscrete Dynamics in Nature and Society, 2022
The current development plans for logistics of city clusters often pursue investment speed, while overlooking the economic benefits of logistics within city clusters.
Qiaoping Zhou   +3 more
doaj   +1 more source

Blockchain Technology Implementation in Logistics

open access: yesSustainability, 2019
This paper researches decentralized data storage represented by blockchain technology and the possibility of its development in sustainable logistics and supply chain management.
E. Tijan   +3 more
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Advances in Inventory Accuracy and Packaging Innovation for Minimizing Returns and Damage in E-Commerce Logistics [PDF]

open access: bronze, 2022
Oyinomomo-emi Emmanuel Akpe   +4 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Weighing the Key Factors to Improve Vietnam's Logistics System

open access: yesAsian Journal of Shipping and Logistics, 2018
Over the past 20 years, Vietnam has signed more free trade agreements than any other country in the region, becoming one of the world's largest integrated economies.
Viet Linh Dang, Gi Tae Yeo
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Evaluating skill requirement for logistics operation practitioners: based on the perceptions of logistics service providers and academics in Taiwan

open access: yesAsian Journal of Shipping and Logistics, 2018
This paper empirically evaluates the crucial dimensions of logistics skill requirements and their discrepancy for logistics operation first line employees from industrial and academic perspectives.
Chi-Chang Lin, Chia-Hsun Chang
doaj   +1 more source

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