Assessing Statistical Methods for Estimating the Cerebrospinal Fluid Early Fungicidal Activity as an Endpoint for Cryptococcal Meningitis Clinical Trials: A Systematic Review and Simulation Study. [PDF]
Fuszard M, Boulware DR, Dai B.
europepmc +1 more source
Contingent capital: A tale of two valuations
Abstract This study investigates the valuation gap between buyers and sellers of insurers' contingent capital, driven by asymmetric exposures to tax benefits, capital injections, and bankruptcy costs. We develop a novel Twin‐Tree Model with Jumps (TTMJ) that models the insurer's asset value dynamics by incorporating catastrophe risk, insolvency risk ...
Tian‐Shyr Dai +3 more
wiley +1 more source
Depower: An R Package for Simulation-Based Power Analysis of Differential Expression Studies. [PDF]
Klamer B, Yu L.
europepmc +1 more source
ABSTRACT The anti‐parasitic drug moxidectin is a frontline treatment for sarcoptic mange in bare‐nosed wombats (Vombatus ursinus), a disease causing significant animal welfare issues and instances of local population declines. Despite widespread usage, knowledge of species‐specific pharmacokinetics of moxidectin in bare‐nosed wombats is still limited ...
E. K. Stott +12 more
wiley +1 more source
The Returns to Education: A Reply
ABSTRACT In this response to Lee Crawfurd's comment on The Returns to Education: A Meta‐Study, we address his three main criticisms. We contend that estimates based on compulsory schooling laws constitute the most reliable evidence on causal returns to education. We show that our parsimonious approach to correcting for publication bias is preferable to
Gregory Clark +1 more
wiley +1 more source
Optimization of tray inventory levels in hospitals from an integral perspective. [PDF]
Bos H +4 more
europepmc +1 more source
On the Exact Limiting Distribution of a Volatility Target Index
ABSTRACT Assuming a lognormal distribution for the underlying risky asset, we study the limiting distribution of a volatility target index as the rebalancing time step approaches zero. Two limit theorems (a strong law of large numbers and a central limit theorem) are established, and as an application, the exact limiting distribution is derived.
Xuan Liu, Michel Gauthier
wiley +1 more source
Ketoanalogue-Supplemented Low-Protein Diet in Patients with Stage 4+ Chronic Kidney Disease in Italy: A Cost-Utility Analysis. [PDF]
De Nicola L +10 more
europepmc +1 more source
ABSTRACT We propose a new model of revenue‐maximising lottery pricing under income‐related heterogeneity and apply it to 13 years of UK National Lottery data. Our pricing rule shows how a state's lottery power is shaped by heterogeneities in lotto demand and the income distribution, and we study its efficiency and distributional implications.
Martin Forster +2 more
wiley +1 more source
Economic evaluation of finotonlimab plus bevacizumab as first-line therapy for advanced hepatocellular carcinoma. [PDF]
Xu X +5 more
europepmc +1 more source

