Results 71 to 80 of about 400,947 (305)

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

open access: yesAdvanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang   +3 more
wiley   +1 more source

Miracles, Trust, and Ennui in Barnes’ Predictivism [PDF]

open access: yes, 2011
Eric Barnes’ The Paradox of Predictivism is concerned primarily with two facts: predictivism and pluralism. In the middle part of the book, he peers through these two lenses at the tired realist scarecrow of the no-miracles argument.
Magnus, P. D.
core   +1 more source

A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat

open access: yesAdvanced Science, EarlyView.
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su   +10 more
wiley   +1 more source

Logo

open access: yesJournal of Physics: Conference Series, 2020
134
openaire   +3 more sources

Using Entropy to Measure Religious Pluralism

open access: yesEntropy
This paper discusses a unique and revolutionary method that quantitatively evaluates the programming of a media outlet regarding religious pluralism. Using a “program appeal” score and entropy measures from information theory, the broadcast operator is ...
George Sturm
doaj   +1 more source

The New Organics Logo for Europe [PDF]

open access: yes, 2010
Europe has a new organics logo from 1 July 2010. The new logo is mandated for all organic produce of Europe. The new logo is the product of a Europe-wide competition which attracted 3,422 entries, of which three were shortlisted and subjected to an ...
Paull, John
core  

Spurious, Emergent Laws in Number Worlds

open access: yes, 2019
We study some aspects of the emergence of logos from chaos on a basal model of the universe using methods and techniques from algorithmic information and Ramsey theories.
Calude, Cristian S., Svozil, Karl
core   +2 more sources

Undaunted Explanationism [PDF]

open access: yes, 2017
Explanationism is a plausible view of epistemic justification according to which justification is a matter of explanatory considerations. Despite its plausibility, explanationism is not without its critics. In a recent issue of this journal T.
McCain, Kevin
core   +1 more source

Cryoablation Activates the cGAS–STING‐CXCL10 Axis in Macrophages to Enhance Anti‐Tumor Immunity in NSCLC

open access: yesAdvanced Science, EarlyView.
Tumor dsDNA released by cryoablation is taken up by macrophages, activating the cGAS‐STING signaling pathway. This leads to an expansion of the CXCL10+ macrophage pool and increased secretion of CXCL10, which in turn recruits CXCR3+ T cells from draining lymph nodes into the tumor microenvironment to exert anti‐tumor effects.
Xinxin Zhi   +17 more
wiley   +1 more source

The fires of change: Kirk, Popper, and the Heraclitean debate [PDF]

open access: yes, 2019
In this paper, I explore a prominent question of Hericlitean scholarship: how is change possible? Karl Popper and G. S. Kirk tackle this same question.
Cooper, Holly
core  

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