Results 121 to 130 of about 1,649 (190)

Novel Antifungal Compounds Discovered in Medicines for Malaria Venture’s Malaria Box

mSphere, 2018
Similarities in fungal and animal cells make antifungal discovery efforts more difficult than those for other classes of antimicrobial drugs. Currently, there are only three major classes of antifungal drugs used for the treatment of systemic fungal ...
Eric H. Jung, David J. Meyers, Jürgen Bosch, Arturo Casadevall   +3 more
doaj   +1 more source

Emerging Fungal Infections of the Central Nervous System in the Past Decade: A Literature Review

Infectious Disease Reports
Introduction: Invasive fungal infections affecting the central nervous system (CNS) are a major health concern worldwide associated with high mortality rates.
Rita Lino, André Rodrigues Guimarães, Estela Sousa, Mariana Azevedo, Lurdes Santos   +4 more
doaj   +1 more source

Olorofim for the treatment of invasive fungal diseases in patients with few or no therapeutic options: a single-arm, open-label, phase 2b study

BackgroundOnly a small number of antifungal therapies for invasive fungal disease (IFD) are currently available, and many pathogens are resistant to one or more of these therapies. Olorofim, the first orotomide antifungal agent to be developed, is active
Aguado, Jose Maria, Alexander, Barbara D, Aoun, Mickael, Bazaz, Rohit, Bruns, Anke H W, Brüggemann, Roger J, Chayakulkeeree, Methee, Chen, Sharon C A, Cornelissen, Karen, Cornely, Oliver A, Dane, Aaron, Donovan, Fariba M, Fitton, Lesley, Fortún, Jesus, Georgala, Aspasia, Hammond, Sarah P, Heath, Christopher H, Hoenigl, Martin, Holland, Steven M., Johnson, Royce, Koehler, Philipp, Maertens, Johan A, Mehra, Varun, Mehta, Sanjay R, Miceli, Marisa H, Morrissey, C Orla, Moussa, Mohamed, Nguyen, M Hong, Ostrosky-Zeichner, Luis, Paterson, David L., Patterson, Thomas F, Plate, Markus, Rahav, Galia, Rex, John H., Richardson, Riina, Rijnders, Bart, Ross, Geoffrey G, Schaenman, Joanna, Schwartz, Stefan, Shoham, Shmuel, Sikka, Monica K, Slavin, Monica A, Sole, Amparo, Spec, Andrej, Thompson, George R, Uspenskaya, Olga, Vazquez, Jose A, Veerdonk, Frank L. van de, Verweij, Paul E, Walsh, Stephen R, Walsh, Thomas J, White, P Lewis, Yehudai-Ofir, Dana, Zinzi, Daniela   +53 more
core   +2 more sources

Antifungal Susceptibility Trends Among Filamentous Fungi: An Epidemiological Evaluation on Aspergillus spp., Fusarium spp., and Scedosporium spp. from Southern Italy

Antibiotics
Background/Objectives: Antifungal resistance among filamentous fungi is an increasing global concern with significant implications for clinical management. Herein, we propose a study aiming to investigate in vitro susceptibility patterns and epidemiology
Maddalena Calvo, Marta Caccamo, Dalila Maria Cammarata, Laura Trovato   +3 more
doaj   +1 more source

Development of new strategies for the treatment of emerging opportunistic fungal infections [PDF]

, 2016
Aspergillus fumigatus és el fong filamentós més freqüent i, encara que normalment és sensible als antifúngics, recentment s’han detectat aïllats resistents.
Martín Vicente, Adela
core   +2 more sources

Identificación de los antígenos reconocidos por sueros humanos sanos en hifas de hongos del grupo Scedosporium/Lomentospora [PDF]

, 2016
La importancia que están tomando las especies emergentes de hongos patógenos L. prolificans, S. apiospermumy S.aurantiacum, junto con el alto grado de virulencia que presentan, hace imprescindible un estudio exhaustivo de
Ugarte Lucas, Paula
core  

Avaliação da atividade do iodoquinol contra fungos dos gêneros Scedosporium e Lomentospora [PDF]

Os fungos dos gêneros Scedosporium e Lomentospora são fungos filamentosos, de hifas septadas e hialinas, saprofíticos e de ampla distribuição no mundo.
Santos, Johnatha de Souza
core  

Pulmonary Scedosporium and Lomentospora infections

, 2015
Yuranga Weerakkody, Liz Silverstone
openaire   +1 more source

The genomes of Scedosporium between environmental challenges and opportunism [PDF]

, 2023
Spina, Federica, Varese, Giovanna Cristina, Venice, Francesco   +2 more
core   +1 more source

Multicenter study demonstrates standardization requirements for mold identification by MALDI-TOF MS [PDF]

, 2019
Burnham, Carey-Ann D, et al,, Lau, Anna F, Mitchell, Kaitlin F, Wallace, Meghan A   +4 more
core   +1 more source