Results 71 to 80 of about 1,376 (185)

Saccharide sources do not influence the biofilm formation in Scedosporium/Lomentospora species [PDF]

Experimental Results, 2020
Abstract Scedosporium and Lomentospora species are ubiquitous saprophytic filamentous fungi that emerged as human pathogens with impressive multidrug-resistance profile.
Thaís Pereira de Mello, Marta Helena Branquinha, André Luis Souza dos Santos, Michael Nevels   +3 more
openaire   +2 more sources

Ibrexafungerp, a Novel Triterpenoid Antifungal in Development for the Treatment of Mold Infections [PDF]

, 2022
Molds are ubiquitous in the environment, and immunocompromised patients are at substantial risk of morbidity and mortality due to their underlying disease and the resistance of pathogenic molds to currently recommended antifungal therapies.
Alastruey-Izquierdo, Ana, Alexander, Barbara, Angulo, David A, Azie, Nkechi E, Ghannoum, Mahmoud A, Hoenigl, Martin, Ibrahim, Ashraf S, King, Thomas R, Rautemaa-Richardson, Riina, Walsh, Thomas J   +9 more
core   +2 more sources

Fusarium species,Scedosporium species, and Lomentospora prolificans: A systematic review to inform the World Health Organization priority list of fungal pathogens [PDF]

Recognizing the growing global burden of fungal infections, the World Health Organization established a process to develop a priority list of fungal pathogens (FPPL).
Al-Nuseirat, Adi, Alastruey-Izquierdo, Ana, Beyer, Peter, Bupha-Intr, Olivia, Cassini, Alessandro, Chiller, Tom M, Colombo, Arnaldo, Dao, Aiken, Denning, David W, Forastiero, Agustina, Fusire, Terence, Garnham, Katherine, Halliday, Catriona L, Hamers, Raph L, Kim, Hannah Yejin, Marinelli, Tina, Morris, Arthur J, Nucci, Marcio, Oladele, Rita, Perfect, John, Ramon-Pardo, Pilar, Rickerts, Volker, Sorrell, Tania C, Wahyuningsih, Retno   +23 more
core   +5 more sources

Autopsy Findings in a Case of Lomentospora prolificans Fungemia in Myelodysplastic Syndrome

Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.
Background Lomentospora prolificans is a soil‐, plant‐, or animal‐borne mold that can affect immunocompromised hosts. Most L. prolificans infections are identifiable in the bloodstream. L. prolificans fungemia has never been reported in an autopsy. Case Report We treated a 79‐year‐old man with myelodysplastic syndrome (MDS), MDS‐EB‐1 subtype.
Osamu Imataki, Yui Kawanaka, Tomoya Ishida, Haruyuki Fujita, Makiko Uemura, Jon Salmanton Garcia   +5 more
wiley   +1 more source

Cyclophilin and enolase are the most prevalent conidial antigens of Lomentospora prolificans recognized by healthy human salivary IgA and cross-react with Aspergillus fumigatus [PDF]

, 2016
Purpose: The study of the immunocompetent airways immune response may provide important information to improve the therapeutic efficacy against Lomentospora (Scedosporium) prolificans. So, this study aimed to identify the most prevalent conidial antigens
Antorán Díaz, Aitziber, Buldain Garriz, Idoia, Hernando Echevarria, Fernando Luis, Pellón Rodríguez, Aize, Ramírez García, Andoni, Rementeria Ruiz, Aitor Domingo, Sevilla, María Jesús   +6 more
core   +1 more source

Antifungal Susceptibility Profiles and Drug Resistance Mechanisms of Clinical Lomentospora prolificans Isolates

Antimicrobial Agents and Chemotherapy, 2020
Lomentospora prolificans is an opportunistic fungal pathogen with low susceptibility to current antifungal drugs. Here, we tested the in vitro susceptibility of 8 drugs against 42 clinical L. prolificans isolates. All isolates showed high MICs to voriconazole (MIC 90
Yongqin Wu, Nina Grossman, Marissa Totten, Warda Memon, Anna Fitzgerald, Chunmei Ying, Sean X. Zhang   +6 more
openaire   +3 more sources

Disseminated Lomentospora prolificans infection that could have been predicted: A case report. [PDF]

IDCases
Lomentospora prolificans is a rare, filamentous fungus, that causes a disseminated infection in immunocompromised individuals. Disseminated infections caused by the fungus are difficult to diagnose early. It is resistant to multiple antifungal agents and has a high mortality rate.
Sato K, Hayashi T, Ishizaki T, Yoshida M, Watanabe A.   +4 more
europepmc   +4 more sources

Repurposing of auranofin and honokiol as antifungals against Scedosporium species and the related fungus Lomentospora prolificans

Virulence, 2021
The slowing-down de novo drug-discovery emphasized the importance of repurposing old drugs. This is particularly true when combating infections caused by therapy-refractory microorganisms, such as Scedosporium species and Lomentospora prolificans. Recent
Hajar Yaakoub, Cindy Staerck, Sara Mina, Charlotte Godon, Maxime Fleury, Jean-Philippe Bouchara, Alphonse Calenda   +6 more
doaj   +1 more source

Identification of Filamentous Fungi: An Evaluation of Three MALDI‐TOF Mass Spectrometry Systems

Mycoses, Volume 68, Issue 6, June 2025.
ABSTRACT Background Identification of filamentous fungi still poses a major challenge to laboratories. Matrix assisted laser desorption/ionisation time of flight mass spectrometry (MALDI‐TOF MS) is a promising tool, since it offers low‐cost and fast results. Different MALDI‐TOF MS systems are available for routine laboratories.
Isabel Klugherz, Bettina Kölli, Moritz Reinmüller, Birgit Willinger, Eva Leitner, Ivo Steinmetz, Karl Dichtl   +6 more
wiley   +1 more source

Invasive Fungal Disease Associated With Targeted Agents for Acute Myeloid Leukaemia: A Systematic Review

eJHaem, Volume 6, Issue 2, April 2025.
ABSTRACT Objective To examine the incidence of invasive fungal disease (IFD) in patients receiving targeted agents for acute myeloid leukaemia (AML). Methods Literature for this systematic review was identified through a PubMed search in April 2024, using AML, IFD and targeted therapy terms.
Samir Agrawal, Anjaneya Bapat, Christopher P. Eades, Shreyans Gandhi   +3 more
wiley   +1 more source