Results 81 to 90 of about 1,649 (190)

Multilocus Sequence Typing Reveals Extensive Genetic Diversity of the Emerging Fungal Pathogen Scedosporium aurantiacum [PDF]

, 2021
Scedosporium spp. are the second most prevalent filamentous fungi after Aspergillus spp. recovered from cystic fibrosis (CF) patients in various regions of the world.
Abdullah, Sarimah, Arthur, Ian, Artigas, Josep Guarro, Blyth, Christopher C., Bouchara, Jean-Philippe, Buzina, Walter, Chen, Sharon C. A., Firacative, Carolina, Fraser, Mark, Gilgado, Felix, Giraud, Sandrine, Harun, Azian, Heath, Christopher H., Kaltseis, Josef, Kan, Alex, Lackner, Michaela, Lira, Jose´ F. Cano, Losert, Heidemarie, Meyer, Wieland, Perdomo, Haybrig, Rainer, Johannes, Schwabenbauer, Katharina, Slavin, Monica A., Tintelnot, Kathrin   +23 more
core   +3 more sources

Treatment of Aspergillosis. [PDF]

, 2018
Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Hoenigl, Martin, Jenks, Jeffrey D
core   +1 more source

Saccharide sources do not influence the biofilm formation in Scedosporium/Lomentospora species [PDF]

Experimental Results, 2020
Abstract Scedosporium and Lomentospora species are ubiquitous saprophytic filamentous fungi that emerged as human pathogens with impressive multidrug-resistance profile.
Thaís Pereira de Mello, Marta Helena Branquinha, André Luis Souza dos Santos, Michael Nevels   +3 more
openaire   +2 more sources

Ibrexafungerp, a Novel Triterpenoid Antifungal in Development for the Treatment of Mold Infections [PDF]

, 2022
Molds are ubiquitous in the environment, and immunocompromised patients are at substantial risk of morbidity and mortality due to their underlying disease and the resistance of pathogenic molds to currently recommended antifungal therapies.
Alastruey-Izquierdo, Ana, Alexander, Barbara, Angulo, David A, Azie, Nkechi E, Ghannoum, Mahmoud A, Hoenigl, Martin, Ibrahim, Ashraf S, King, Thomas R, Rautemaa-Richardson, Riina, Walsh, Thomas J   +9 more
core   +2 more sources

Cyclophilin and enolase are the most prevalent conidial antigens of Lomentospora prolificans recognized by healthy human salivary IgA and cross-react with Aspergillus fumigatus [PDF]

, 2016
Purpose: The study of the immunocompetent airways immune response may provide important information to improve the therapeutic efficacy against Lomentospora (Scedosporium) prolificans. So, this study aimed to identify the most prevalent conidial antigens
Antorán Díaz, Aitziber, Buldain Garriz, Idoia, Hernando Echevarria, Fernando Luis, Pellón Rodríguez, Aize, Ramírez García, Andoni, Rementeria Ruiz, Aitor Domingo, Sevilla, María Jesús   +6 more
core   +1 more source

Antifungal Susceptibility Profiles and Drug Resistance Mechanisms of Clinical Lomentospora prolificans Isolates

Antimicrobial Agents and Chemotherapy, 2020
Lomentospora prolificans is an opportunistic fungal pathogen with low susceptibility to current antifungal drugs. Here, we tested the in vitro susceptibility of 8 drugs against 42 clinical L. prolificans isolates. All isolates showed high MICs to voriconazole (MIC 90
Yongqin Wu, Nina Grossman, Marissa Totten, Warda Memon, Anna Fitzgerald, Chunmei Ying, Sean X. Zhang   +6 more
openaire   +3 more sources

Identification of Filamentous Fungi: An Evaluation of Three MALDI‐TOF Mass Spectrometry Systems

Mycoses, Volume 68, Issue 6, June 2025.
ABSTRACT Background Identification of filamentous fungi still poses a major challenge to laboratories. Matrix assisted laser desorption/ionisation time of flight mass spectrometry (MALDI‐TOF MS) is a promising tool, since it offers low‐cost and fast results. Different MALDI‐TOF MS systems are available for routine laboratories.
Isabel Klugherz, Bettina Kölli, Moritz Reinmüller, Birgit Willinger, Eva Leitner, Ivo Steinmetz, Karl Dichtl   +6 more
wiley   +1 more source

Invasive Fungal Disease Associated With Targeted Agents for Acute Myeloid Leukaemia: A Systematic Review

eJHaem, Volume 6, Issue 2, April 2025.
ABSTRACT Objective To examine the incidence of invasive fungal disease (IFD) in patients receiving targeted agents for acute myeloid leukaemia (AML). Methods Literature for this systematic review was identified through a PubMed search in April 2024, using AML, IFD and targeted therapy terms.
Samir Agrawal, Anjaneya Bapat, Christopher P. Eades, Shreyans Gandhi   +3 more
wiley   +1 more source

Assessing the potential risk of human pathogen resistance to medical antifungal treatments arising from agricultural use of fungicides with the same mode of action

Plant Pathology, Volume 74, Issue 2, Page 578-594, February 2025.
A mechanistic basis is described for assessment of resistance risk to medical antifungal treatments from agricultural use of fungicides of the same mode of action. Abstract A mechanistic basis is described for assessment of resistance risk to medical antifungal treatments from agricultural use of fungicides of the same mode of action.
Neil Paveley, Frank van den Bosch, Michael Grimmer   +2 more
wiley   +1 more source

Infections caused by Scedosporium/Lomentospora species: Clinical and microbiological findings in 21 cases [PDF]

Medical Mycology, 2017
The clinical and microbiological characteristics of infections caused by Scedosporium/ Lomentospora species in 21 patients are described. We searched retrospectively the records for Scedosporium/ Lomentospora species seen at the University Hospital Virgen de las Nieves from 2006 to 2017. Out of them, 16 were male; mean age at diagnosis was 57.8 (±SD 15)
Cobo, Fernando, Lara-Oya, Ana, Rodríguez-Granger, Javier, Sampedro, Antonio, Aliaga-Martínez, Luis, Navarro-Marí, José María   +5 more
openaire   +3 more sources