Results 41 to 50 of about 1,072 (146)
Role of Iron Availability in Modulating Pseudomonas aeruginosa’s Antifungal Effects on Planktonic and Biofilm Growth of Scedosporium/Lomentospora Under Cystic Fibrosis-Mimicking Conditions [PDF]
Pseudomonas aeruginosa and Scedosporium/Lomentospora often coexist in the lungs of cystic fibrosis patients, where their interaction can affect disease outcomes. Our group has recently demonstrated that P. aeruginosa suppresses the growth of Scedosporium/
Thaís P. Mello +6 more
doaj +2 more sources
Background and aims. Scedosporium species and Lomentospora prolificans are the filamentous fungi isolated more frequently from the cystic fibrosis (CF) lower airways, after Aspergillus fumigatus. Previous studies showed that, in CF patients, Scedosporium
Lisa Cariani +14 more
doaj +1 more source
Invasive Scedosporium and Lomentospora prolificans Infections in Australia: A Multicenter Retrospective Cohort Study. [PDF]
AbstractBackgroundManagement of Scedosporium/Lomentospora prolificans infections remains challenging. We described predisposing factors, clinical manifestations, and outcomes of these rare mold infections, including predictors of early (1-month) and late (18-month) all-cause mortality and treatment failure.MethodsWe conducted a retrospective Australian-
Neoh CF +9 more
europepmc +3 more sources
Antifungal Susceptibility Profiles and Drug Resistance Mechanisms of Clinical Lomentospora prolificans Isolates. [PDF]
Lomentospora prolificans is an opportunistic fungal pathogen with low susceptibility to current antifungal drugs. Here, we tested the in vitro susceptibility of 8 drugs against 42 clinical L. prolificans isolates. All isolates showed high MICs to voriconazole (MIC 90
Wu Y +6 more
europepmc +4 more sources
Lomentospora prolificans endocarditis - case report and literature review [PDF]
Lomentospora prolificans (formally Scedosporium prolificans) is an environmental mould with a global distribution. Endocarditis caused by L. prolificans is a rare but serious emerging disease in immunocompromised patients. Prior to this case there have only been eight cases reported in the literature.
Kelly, M, Stevens, R, Konecny, P
openaire +3 more sources
Abstract Rhinocladiella mackenziei is a highly neurotropic fungus, mainly reported from the Middle East. However, in recent years, there have been some cases from outside this region. We described an additional fatal case of R. mackenziei cerebral infection for the first time from Turkey and made a literature review of all previously reported cases ...
Ilvana Caklovica Kucukkaya +6 more
wiley +1 more source
Abstract Scedosporium and Lomentospora species are environmental moulds that are virulent in immunocompromised hosts and rarely cause bloodstream infection (BSI). Patients with Scedosporium and Lomentospora species BSI were identified by the state public laboratory service in Queensland, Australia, over a 20‐year period.
Adam G. Stewart +5 more
wiley +1 more source
Abstract Objective The infection risk in patients receiving ibrutinib, idelalisib or venetoclax for chronic lymphocytic leukaemia (CLL) or B‐cell lymphoma treated outside of clinical trials is incompletely defined. We sought to identify the severe infection rate and associated risk factors in a ‘real‐world’ cohort.
Amanda Tey +7 more
wiley +1 more source
Pathogen‐specific T Cells: Targeting Old Enemies and New Invaders in Transplantation and Beyond
Adoptive immunotherapy with virus‐specific cytotoxic T cells (VSTs) has evolved over the last three decades as a strategy to rapidly restore virus‐specific immunity to prevent or treat viral diseases after solid organ or allogeneic hematopoietic cell‐transplantation (allo‐HCT).
Anastasia Papadopoulou +4 more
wiley +1 more source
Voriconazole‐Associated Periostitis: New Insights into Pathophysiology and Management
ABSTRACT Voriconazole‐associated periostitis (VAP) is an underrecognized and unpredictable side effect of long‐term voriconazole therapy. We report two cases of VAP occurring in the post‐transplant setting: a 68‐year‐old lung transplant recipient who required ongoing voriconazole therapy, in whom urinary alkalinization was used to promote fluoride ...
Michael J Bennett +9 more
wiley +1 more source

