Results 211 to 220 of about 8,614,135 (311)

Interactive workshops on improving dental students' understanding of environmentally sustainable dentistry: a quality improvement project. [PDF]

BDJ Open
Mai F, Parkinson E, Mumford F, Shehabi Z.   +3 more
europepmc   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

Annual and Daily Changes of Thunderstorms in Temperate Climate in London, Warsaw and Moscow

Miscellanea Geographica: Regional Studies on Development, 2011
Grabowska Katarzyna
doaj   +1 more source

Interpreting Blood Transfusion in Hip Fracture Surgery: Marker of Severity Rather Than Mediator of Harm? [Letter]. [PDF]

J Blood Med
Ahmad A, Harris BHL, Fertleman MB, Koizia LJ.   +3 more
europepmc   +1 more source

Design of Optical Transducer for Recognition of Biomolecular Interactions between Bacterial Lipopolysaccharides and Amino Acids

Advanced Science, EarlyView.
A deep comprehension of biomolecular phenomena at interfaces is significant with their fundamental and practical importance. Our experimental and theoretical investigations reveal that specific amino acids (glutamic acid and aspartic acid) exhibit an orientational coupling with liquid crystals, which can recognize and optically report the interfacial ...
Yena Choi, Sangmin Lee, Jin‐Kang Choi, Hyunsoo Han, Yeongseon Choi, Jun‐Hyung Im, Hyein Kim, Sangmin Jeon, Minjae Lee, Chang Yun Son, Young‐Ki Kim   +10 more
wiley   +1 more source

A novel methodology using direct patient contact and UK national registries to collect long-term data from randomised trials: TARGIT-X - an extended follow-up study of the TARGIT-A trial of targeted intraoperative radiotherapy for breast cancer.

Health Technol Assess
Vaidya JS, Williams NR, Bulsara M, Brew-Graves C, Potyka I, Roberts N, Lindsay J, Laws S, Raj S, Douek M, Falzon M, Petralia G, Needleman S, Malhotra A, Bernstein M, Tobias JS.   +15 more
europepmc   +1 more source

Cesarean Anesthesia Type and Neonatal Outcomes: Comment. [PDF]

Anesthesiology
Craig R, O'Carroll JE, Lucas N, Landau R, Habib AS, Carvalho B.   +5 more
europepmc   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Integrating tuberculosis control into maternal and newborn health services during pregnancy and postpartum is an urgent priority. [PDF]

PLOS Glob Public Health
Okomo U, Nkereuwem E, Blencowe H, Banke-Thomas A, Togun T.   +4 more
europepmc   +1 more source