Results 221 to 230 of about 8,614,135 (311)

Temporal Interference Stimulation Enhances Neural Regeneration

Advanced Science, EarlyView.
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressott, Maria Garcia Garrido, Patrycja Dzialecka, Rachel Man Hoi Law, Roberto Portillo‐Lara, Bethany Geary, Elena Faillace, Shirine Merlo‐Nikpay Aslie, Marcelina Wojewska, Maria Otero‐Jimenez, Martina Genta, Luqiao Tan, Karen Duff, Javier Alegre‐Abarrategui, Rylie Green, Nir Grossmann   +15 more
wiley   +1 more source

Publisher Correction: Engineering modular and orthogonal genetic logic gates for robust digital-like synthetic biology. [PDF]

Nat Commun
Wang B, Kitney RI, Joly N, Buck M.
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Unpacking uncertainty in polygenic risk scores: Playing "risk score roulette". [PDF]

J Alzheimers Dis
Koizia LJ, Allott VES, Harris BHL.
europepmc   +1 more source

In Situ Electrochemical Activation of Pseudo‐Layered NbS3 via Interlayer Expansion and Dual Redox for High Mg‐Ion Storage

Advanced Science, EarlyView.
A quasi‐1D pseudo‐layered NbS3 cathode for magnesium‐ion batteries can be created through electrochemically induced interlayer expansion. The widened ion‐transport channels enable fast magnesium ion diffusion and unlock coupled cationic‐anionic redox chemistry.
Pengcheng Jing, Atsushi Inoishi, Chengcheng Zhao, Eiichi Kobayashi, Peng Ren, Isaac Abrahams, Duncan H. Gregory   +6 more
wiley   +1 more source

Outcomes in Children With Enterovirus Meningitis in London, England: A Retrospective Multicenter Cohort Study, 2013-2023. [PDF]

Open Forum Infect Dis
Broad J, Zombori L, Bravo Queipo-de-Llano B, Bamford A, Best T, Cohen J, Drysdale SB, Manian A, Soni N, Whittaker E, Kadambari S.   +10 more
europepmc   +1 more source

Enzymatic Basis for the Oxidative Branch of Aromatic Amino Acid Fermentation Leading to p‐cresol Formation

Advanced Science, EarlyView.
In anaerobic bacteria, tyrosine serves as an electron donor in the oxidative Stickland fermentation branch, generating p‐hydroxyphenylacetate, ATP and reduced ferredoxin for decarboxylation into p‐cresol. ABSTRACT The phenolic metabolite p‐cresol is a byproduct of tyrosine fermentation by certain strictly anaerobic bacteria, including the human gut ...
Li Jiang, Yifeng Wei, Xumei Liu, Dazhi Liu, Zhenyu Liu, Yang Tong, Jinyu Yin, Ankanahalli N. Nanjaraj Urs, Meining Xing, Mark A. Harrison, Chuyuan Zhang, Sheng Yang, Yunzi Luo, Ee Lui Ang, Huimin Zhao, Yan Zhang   +15 more
wiley   +1 more source

Setting the research priorities for pregnancy scanning: a nationally coproduced vision with expectant women, the public and healthcare professionals. [PDF]

Br J Radiol
Matthew J, Watty S, Nihouarn Sigurdardottir J, Malamateniou C, Skelton E, Barry Z, Rutherford M, Silverio SA, Story L.   +8 more
europepmc   +1 more source

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li, Yajin Liao, Yan‐bo Zhao, Hongxing Wu, Tong Jin, Shuoshuo Li, Yuhan Liu, Peng Li, Songying Ouyang, Zekai Li, YuTing Xia, Qian Hua, Rui‐Yuan Pan, Zengqiang Yuan   +13 more
wiley   +1 more source

Visualizing pathology: The development of a narrated video autopsy for medical students. [PDF]

Acad Pathol
Wraith C, Osborn M, Meeran K, Sam AH.
europepmc   +1 more source