Results 41 to 50 of about 8,614,135 (311)

Introduction : screen Londons [PDF]

, 2009
Our aim, in editing the ‘London Issue’ of this journal, is to contribute to a conversation between scholars of British cinema and television, London historians and scholars of the cinematic city.
Barefoot G., Billig M., Billingham P., Bruno G., Charlotte Brunsdon, Charney L., Clarke D., Cunningham G., Dave P., Hallam J, Hansen M., Harvey D., Huyssen A., Jousse T., Klein N., Konstantarakos M., Krause L., Leonard M., Martin-Jones D., Mazierska E., Mellor D., Mort F., Murphy R., Nead L., Orr J., Petit C., Sandbrook D., Sandhu S., Shiel M., Stewart J., Warshow R., Webber A.   +31 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

London’s foundations protecting the geodiversity of the capital [PDF]

, 2009
This report describes a geodiversity audit of London commissioned by a partnership led by the Greater London Authority (GLA), which includes the British Geological Survey (BGS), Natural England, Government Office for London, London Biodiversity ...
Aldiss, Don, Barron, Hugh, Harrison, Anna, Thompson, Joanna, Woods, Mark   +4 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Migration: A Process of Search - London A Case Study

Populasi
TV news, social media, and newspapers continue presenting migrants as a threat to the rich economies. However, the richness of cosmopolitan cities is the migration. London, the capital of the United Kingdom, is a case in point.
Nubia Zulma Nieto Flores
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Strategies of personification of the image of London: From binary conflicts to systems

Urbis et Orbis: Mikroistoriâ i Semiotika Goroda, 2023
The article is devoted to the city of London as one of the main topoi of British literature. London acquires the status of a central image in the Victorian novel where its anthropomorphism is created by binary conflicts of richness and poverty, splendor ...
Natalia Zelezinskaya
doaj   +1 more source

Engendering city politics and educational thought: elite women and the London Labour Party, 1914-1965 [PDF]

, 2008
This article uses biographical approaches to recover the contribution of hitherto neglected figures in the history of education and the political history of the Left in London.
Martin, Jane
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Learning what high quality compassionate care means for cancer patients and translating that into practice

Patient Experience Journal, 2014
In 2010, UCLPartners, a partnership of health care providers and universities in North Central London, began a collaboration with local commissioners that aimed to think about cancer care and diagnosis differently.
Fiona McKenzie, Katherine Joel, Charlotte Williams, Kathy Pritchard-Jones   +3 more
doaj