Results 41 to 50 of about 3,420,995 (285)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Управленческое консультирование, 2021 The UK is one of the leaders in the use of digital tools in the interaction of government institutions and citizens. Now we are witnessing an active dialogue between various British institutions precisely in the digital dimension, as the transfer of data
N. V. Eremina
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Calendar of London Concerts 1750-1800
, 2019 The calendar contains records of over 4000 concerts, advertised in London daily newspapers from 1750 to 1800: subscription concerts, benefits, oratorio performances, meetings of musical societies, concerts at the principal gardens. Information on concert
McVeigh, Prof S. (Goldsmiths, University of London), ProjectLeader
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The making of Polish London through everyday life, 1956-1976 [PDF]
, 2009 The wartime and postwar Polish emigration allows us to study a ‘parallel’ history of the Polish nation. Poles in Great Britain were free from the restrictions imposed on Poles in the homeland by the communist dictatorship; they were thus better able ...
Chojnacki, P, Chojnacki, P.
core
"THE LONDON COUNTY COUNCIL AND INSANITY IN LONDON." [PDF]
The Lancet, 1896 n ...
openaire +2 more sources
Migration: A Process of Search - London A Case Study
PopulasiTV news, social media, and newspapers continue presenting migrants as a threat to the rich economies. However, the richness of cosmopolitan cities is the migration. London, the capital of the United Kingdom, is a case in point.
Nubia Zulma Nieto Flores
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source