Results 51 to 60 of about 1,860,532 (267)
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Fortunato Chelleri’s Cantate e arie con stromenti (1727): A souvenir of London
De Musica Disserenda, 2015 The Italian composer and instrumentalist Fortunato Chelleri paid three visits to London between 1725 and 1728. Although he failed to have any of his operas performed there, he distinguished himself as a harpsichordist and cellist and left a permanent ...
Michael Talbot
doaj +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Houseplants in Basildon: Urban Precarity, Class and Housing in Oisín McKenna’s Evenings and Weekends
Anglo SaxonicaOisín McKenna’s Evenings and Weekends explores urban precarity within London’s housing crisis, framing class as embodied in characters’ bodies and futures.
Diana Ortega Martin
doaj +1 more source
Nordic Ties and British Lives? Migrant Capital and the Case of Nordic Migrants Living in London
Social Inclusion, 2019 As a hub of finance, art, design and science, the city of London has long attracted migrants interested in study and career opportunities or simply excited about living in an open, global city.
Saara Koikkalainen
doaj +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source