Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
“Frockcoats Walking in Line”: Noguchi Yonejirō’s Perception of Edwardian London
Ежегодник ЯпонияThis article is devoted to the construction of the image of London and Londoners in the early 20th century in the works of a Japanese writer and poet Noguchi Yonejirō (1875–1947) on his first trip to Britain in late 1902.
A. S. Gorbachenko
doaj +1 more source
Planning for residential ‘value’? London’s densification policies and impacts
Buildings & Cities, 2021 This paper considers the agency and influence of planning processes and densification policies on urban landscapes in London. Urban transformation through residential densification can bring opportunities for real estate development, combined with longer
Nicola Livingstone +2 more
doaj +1 more source
Ken Livingstone: “Londoners need a city where they can make their home, feel safe and not be priced out” [PDF]
, 2012 Labour candidate for the London Mayor Ken Livingstone discusses his plans to introduce a London-wide education maintenance allowance, campaign for a London ‘Living Rent’ and to resign within six months if he has not achieved his goals to cut public ...
Livingstone, Ken
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Rotating Superconductors and the Frame-independent London Equation
, 1998 A frame-independent, thermodynamically exact London equation is presented, which is especially valid for rotating superconductors. A direct result is the unexpectedly high accuracy ($\sim10^{-10}$) for the usual expression of the London moment.Comment: 4
A. J. Leggett +24 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Predicting reading recovery selection and outcomes : is it possible? : a thesis presented in partial fulfilment of the requirements for the degree of Master of Education (Literacy) at Massey University, Manawatū, New Zealand [PDF]
, 2017 Purpose: Predictive early literacy assessments are useful to identify students who are at risk of reading difficulty. This study investigated the use of six early literacy assessments, administered when students first entered school (Time 1), and in the ...
London, Athena
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FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Fortunato Chelleri’s Cantate e arie con stromenti (1727): A souvenir of London
De Musica Disserenda, 2015 The Italian composer and instrumentalist Fortunato Chelleri paid three visits to London between 1725 and 1728. Although he failed to have any of his operas performed there, he distinguished himself as a harpsichordist and cellist and left a permanent ...
Michael Talbot
doaj +1 more source
The Changing World of Work: What Should We Ask of Higher Education? [PDF]
, 2015 There is a pervasive anxiety in America about the future of higher education. Spiraling costs combined with seismic changes in the American workplace raise questions about whether a bachelor's degree is still worth the cost.
Scott London
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