Results 51 to 60 of about 409,714 (313)
Loneliness: A Concept Analysis [PDF]
, 2008 TOPIC. Loneliness is a universal human experience recognized since the dawn of time, yet it is unique for every individual. Loneliness can lead to both depression and low self‐esteem. PURPOSE. This article explicates the concept of loneliness through the
Bekhet, Abir K. +1 more
core +1 more source
An exploration of the value and mechanisms of befriending for older adults in England [PDF]
, 2011 Social isolation and loneliness in older adults are growing problems. Empirical research suggests that loneliness can lead to poorer health outcomes including higher mortality rates.
Chew-Graham, Carolyn +4 more
core +1 more source
Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants
Advanced Science, EarlyView.The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann +11 more
wiley +1 more source
The Influence of Loneliness on Pain Outcomes for Adolescents: A Cross-Sectional Survey
Canadian Journal of PainBackground Loneliness, the perception that one’s social relationships do not meet the desire for social connection, is a risk factor for poor mental and physical health.
Paula A. Forgeron +13 more
doaj +1 more source
Creating a virtual support group in an interactive narrative:a companionship game for cancer patients [PDF]
, 2018 Over one in five cancer patients are affected by feelings of loneliness [1]. This paper proposes a text-based game aimed at affected cancer patients, in which the player develops relationships with non-player characters in the context of a fictitious ...
S Chen, T Adlin
core +2 more sources
Advanced Science, EarlyView.The TopCas platform utilizes an engineered DNA‐RNA chimeric circular crRNA to establish topology‐gated control over CRISPR‐Cas12a activity, enabling target‐triggered self‐catalytic amplification (preamplification‐free). This system seamlessly integrates highly sensitive molecular diagnostics with conditionally controlled gene editing, demonstrating ...
Shun Zhang +7 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Blood‐based liquid biopsies hold transformative potential for non‐invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating diverse cancer‐associated responses, represent a compelling yet largely unexplored alternative.
Yan Ma +28 more
wiley +1 more source
Frontiers in PsychologyObjectiveThe De Jong Gierveld Loneliness Scale (DJGLS) has been widely used to measure two types of loneliness: social and emotional loneliness. However, no Japanese translation has been developed. Furthermore, the characteristics of social and emotional
Honami Arai, Sho Okawa
doaj +1 more source
Psychological distress after stroke and aphasia: the first six months [PDF]
, 2010 Objective: We explored the factors that predicted psychological distress in the first six months post stroke in a sample including people with aphasia. Design: Prospective longitudinal observational study.
Ames, D. +6 more
core +1 more source
Advanced Science, EarlyView.Floral meristem (FM) activity is crucial for the initiation of floral organs. In this study, SE represses IPT7 expression and cytokinin signaling via both the miR171c‐5p–KNAT2 and miR164c–CUC1/2–KNAT2 regulatory modules, thereby repressing FM activity. In contrast, STM induces both KNAT2 and IPT7 expression.
Wen Yang +11 more
wiley +1 more source