Results 101 to 110 of about 7,203,816 (245)

Vascular effects of rapid-acting insulin analogs in the diabetic patient: a review

, 2009
Steve Fordan, Philip RaskinDepartment of Medicine, Division, of Endocrinology, University of Texas, Southwestern Medical Center, Dallas, TX, USAAbstract: The insulin analogs lispro, aspart, and glulisine are the only commercially available rapid-acting ...
Steve Fordan, Philip Raskin
core  

2D Skeletal Muscle Thin Film Actuators Enhance Efficiency of Biohybrid Robots

Advanced Functional Materials, EarlyView.
2D skeletal muscle thin film actuators generate millinewton‐scale forces and millimeter‐scale strokes while remaining functional for over 30 days. Their force density is 20‐fold higher than 3D skeletal muscle actuators, enabling multi‐fin robots with tunable speed and multidirectional steering.
Maheera Bawa, Arielle Berman, Laura Schwendeman, Ferdows Afghah, Seanbiron Johnson, Ritu Raman   +5 more
wiley   +1 more source

Long-acting Insulin Analogues and Diabetic Retinopathy: A Retrospective Cohort Study

, 2017
Purpose: Long-acting insulin analogues were developed to facilitate consistent glycemic control without excessive hypoglycemia. However, structural modifications of the insulin molecule can alter biological responses and binding characteristics with ...
Lin, Jen-Chieh;Shau, Wen-Yi;Lai, Mei-Shu, 賴美淑   +1 more
core   +1 more source

An Integrated Oxygen‐Supplying Device and Predictive Multiphysics Model for Extended Ambient Transport of Insulin‐Producing Cells

Advanced Functional Materials, EarlyView.
Cell therapies typically rely on cold‐chain logistics and cryopreservation, limiting access and compromising cell quality. Here, a dual‐chamber device separates an oxygen‐supplying chamber from a hyaluronic acid cargo chamber, sustaining oxygen delivery for over 70 h and enabling ambient‐temperature shipment.
Daniel A. Domingo‐Lopez, Ruth Tarpey, Benjamin Brennan, Bryan D. Boyle, Amir M. Alsharabasy, Abhik Mallick, Gabriella Bellavia, Abhay Pandit, Garry P. Duffy, Ruth E. Levey   +9 more
wiley   +1 more source

Guanosine‐Quadruplex Hydrogels as Dynamic, Mechanically Tunable and Ion Conductive 3D Scaffolds for Cell Culture Applications

Advanced Functional Materials, EarlyView.
Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur, Minye Jin, Pavel Milkin, Deepa Negi, Carla Cofiño Fabres, Hubert Gojzewski, Leonid Ionov, Alla Synytska, Andries van der Meer, Robert Passier, Julieta I. Paez   +10 more
wiley   +1 more source

From economics to health outcomes: Delving into the significance of reduced insulin prices

South African Medical Journal
The recent substantial price reductions in insulin therapy by major manufacturers prompt an examination of their impact on South Africa (SA)’s healthcare.
M Leuschner, M Strydom, V Steenkamp
doaj   +1 more source

Evidence to decision framework “should long-acting insulin analogs vs. human insulin be used for diabetes?”.

Evidence to decision framework “should long-acting insulin analogs vs. human insulin be used for diabetes?”.
Rita Banzi (2473735), Holger J. Schünemann (7804118), Thomas Piggott (9385535), Carlos A. Cuello Garcia (17775548), Elie A. Akl (7776128), Tamara Kredo (417544), Lorenzo Moja (29430), Benedikt Huttner (322756), John N. Lavis (8569008)   +8 more
core   +1 more source

Profil penggunaan insulin long acting pada pasien diabetes melitus tipe 2 di RSUD Kabupaten Sidoarjo [PDF]

, 2018
Diabetes Mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia due to the effects of insulin secretion, or because of the workings of insulin or both.
Lumban Radja, Helen
core  

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source