Results 31 to 40 of about 7,203,816 (245)

Comparison of Prevailing Insulin Regimens at Different Time Periods in Hospitalized Patients: A Real-World Experience from a Tertiary Hospital [PDF]

Diabetes & Metabolism Journal, 2022
Background Prevailing insulin regimens for glycemic control in hospitalized patients have changed over time. We aimed to determine whether the current basal-bolus insulin (BBI) regimen is superior to the previous insulin regimen, mainly comprising split ...
Sun Joon Moon, Hun Jee Choe, Soo Heon Kwak, Hye Seung Jung, Kyong Soo Park, Young Min Cho   +5 more
doaj   +1 more source

Analysis of the quality of life of patients with type 1 diabetes mellitus in real clinical practice who received insulin degludec

Медицинский совет, 2021
Introduction. Long-term and high-quality glycemic control prevents the development of vascular complications of diabetes type 1 and improves the disease prognosis, significantly increasing life expectancy.
L. A. Suplotova, A. S. Sudnitsyna, N. V. Romanova   +2 more
doaj   +1 more source

Drug review - insulin glargine: a long acting insulin analog

, 2005
The main goal of treatment of diabetes mellitus (DM) is to maintain long term near normoglycemia. Insulin therapy plays a pivotal role in the management of DM.
P. N. Chakkarwar, N. A. Manjreka
core   +3 more sources

Efficacy and safety of insulin lispro protamine suspension as basal supplementation in patients with type 2 diabetes

Therapeutic Advances in Endocrinology and Metabolism, 2012
The three currently marketed long-acting insulin analogs, glargine, detemir and insulin lispro protamine suspension (ILPS), represent the most significant advances in basal insulin supplementation since the 1940s and 1950s and the introduction of the ...
Dario Giugliano, Katherine Esposito
doaj   +1 more source

Cancer risk associated with insulin glargine among adult type 2 diabetes patients--a nationwide cohort study. [PDF]

PLoS ONE, 2011
BACKGROUND: Preclinical and observational studies raise the concern about the safety of insulin glargine in terms of cancer initiation and promotion.
Chia-Hsuin Chang, Sengwee Toh, Jou-Wei Lin, Shu-Ting Chen, Chuei-Wen Kuo, Lee-Ming Chuang, Mei-Shu Lai   +6 more
doaj   +1 more source

Improvement of insulin response in the streptozotocin model of insulin-dependent diabetes mellitus. Insulin response with and without a long-acting insulin treatment

Animal, 2009
Streptozotocin-induced diabetes mellitus (STZ-DM) in rats is a model of type 1 diabetes, which is commonly used to study diabetes, but differs from human diabetic pathophysiology in its insulin resistance. An STZ-DM rat can be administered five times the
L. Nordquist, M. Sjöquist
doaj   +1 more source

Role of Myotonic Dystrophy Protein Kinase [DMPK] in Glucose Homeostasis and Muscle Insulin Action [PDF]

, 2007
Myotonic dystrophy 1 (DM1) is caused by a CTG expansion in the 3′-unstranslated region of the DMPK gene, which encodes a serine/threonine protein kinase. One of the common clinical features of DM1 patients is insulin resistance, which has been associated
Liesa Marc, Ciaraldi, Theodore P, Martí, Luc, Ciaraldi, Theodore P., Palacin, Manuel, Catalucci, Daniele, Wolfgang H Dillmann, Esther Llagostera, Perla Kaliman, Catalucci Daniele, Camps, Marta, Reddy, Sita, Gomis, Ramon, 1946-, Luc Marti, Llagostera Martín, Esther, Antonio Zorzano, Ciaraldi Theodore P., Dillmann, Wolfgang H, Llagostera Esther, Gomis Ramon, Reddy Sita, Camps Marta, Dillmann, Wolfgang H., Kaliman Perla, Sita Reddy, Kaliman, Perla, Ruiz-Lozano Pilar, Llagostera, Esther, Richard Kondo, Ruiz-Lozano, Pilar, Zorzano Olarte, Antonio, Manuel Palacin, Zorzano Antonio, Kondo, Richard, Palacín Prieto, Manuel, Ramon Gomis, Daniele Catalucci, Liesa Torre-Marín, Montserrat, Dillmann Wolfgang H., Marti Luc, Camps Camprubí, Marta, Zorzano, Antonio, Marta Camps, Pilar Ruiz-Lozano, Liesa, Marc, Kondo Richard, Gomis, Ramon, Marc Liesa, Theodore P Ciaraldi, Palacin Manuel   +49 more
core   +2 more sources

Availability and use of long-acting insulin analogues including their biosimilars across Africa; findings and implications [PDF]

, 2021
Background: Prevalence rates of diabetes mellitus are growing across Africa with an appreciable number likely to be on insulin to manage their condition. This has significant implications on future morbidity and mortality exacerbated by high complication
Kurdi, Amanj, Sefah, Israel, Njeri, Lisper Wangeci, Alutuli, Luke, Adwubi, Eunice Twumwaa, Abubakar, Abdullahi Rabiu, Phiri, Henry, Acolatse, Joseph, Kalemeera, Francis, Piloya-Were, Thereza, Ogunleye, Olayinka, Godman, Brian, Matowa, Patrick, Malande, Oliver Ombeva, Chikowe, Ibrahim, Chaibva, Blessmore Vimbai, Hango, Ester, Campbell, Stephen, Amu, Adefolarin A, Opanga, Sylvia, Sani, Ibrahim Haruna, Rwegerera, Godfrey Mutashambara, Incoom, Robert, Patrick, Okwen, Zaranyika, Trust, Allocati, Eleonora, Khuluza, Felix, Kimonge, David, Ibrahim, Kamilou, Haque, Mainul, Leong, Trudy, Lum Niba, Loveline, Kibuule, Dan, Kalungia, Aubrey Chichonyi, Oluka, Margaret   +34 more
core   +2 more sources

Development of AIDA v4.3b Diabetes Simulator: Technical Upgrade to Support Incorporation of Lispro, Aspart, and Glargine Insulin Analogues

Journal of Electrical and Computer Engineering, 2011
Introduction. AIDA is an interactive educational diabetes simulator available on the Internet without charge since 1996 (accessible at: http://www.2aida.org/).
Eldon D. Lehmann, Cristina Tarín, Jorge Bondia, Edgar Teufel, Tibor Deutsch   +4 more
doaj   +1 more source

The Price Paradox of Biosimilar-Like Long-Acting Insulin

, 2022
Objectives: To describe the uptake and out-of-pocket (OOP) costs of Basaglar, the first long-acting insulin biosimilar, in a commercially insured population in the United States.
Mouslim, Morgane, Trujillo, Antonio J., Rashidi, Emaan S., Levy, Joseph F., Socal, Mariana P.   +4 more
core   +1 more source