Results 91 to 100 of about 11,289,407 (322)

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Patient characteristics associated with clinically coded long COVID: an OpenSAFELY study using electronic health records [PDF]

Background Clinically coded long COVID cases in electronic health records are incomplete, despite reports of rising cases of long COVID. Aim To determine patient characteristics associated with clinically coded long COVID.
Bacon, Sebastian, Cezard, Genevieve, Chaturvedi, Nish, Davy, Simon, Denaxas, Spiros, Denholm, Rachel, Fisher, Louis, Goldacre, Ben, Greaves, Felix, Horne, Elsie Mf, Knight, Rochelle, Macleod, John, Mehrkar, Amir, Riley, Stephanie, Sheikh, Aziz, Silverwood, Richard J, Sterne, Jonathan, Steves, Claire, Taylor, Kurt, Walker, Alex J, Walker, Venexia, Wei, Yinghui, Willans, Robert, Williams, Dylan M, Wood, Angela M   +24 more
core   +2 more sources

Socioeconomic Challenges Of Long Covid [PDF]

, 2023
Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection or PASC, is a condition resulting from a SARS-CoV-2 infection characterized by continuing or novel symptoms across multiple organ systems occurring at least four weeks after infection.
Catt, Justin
core   +1 more source

Long COVID: clues about causes

European Respiratory Journal, 2023
Many patients report persistent symptoms after resolution of acute COVID-19, regardless of SARS-CoV-2 variant and even if the initial illness is mild [1, 2]. A multitude of symptoms have been described under the umbrella term ‘Long COVID’, otherwise known as ‘post-COVID syndrome’ or ‘post-acute sequelae of SARS-CoV-2 (PASC)’; for simplicity we will use
Felicity Liew, Claudia Efstathiou, Peter J.M. Openshaw   +2 more
openaire   +2 more sources

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Barriers to healthcare access and experiences of stigma: Findings from a coproduced Long Covid case‐finding study

Health Expectations
Background and Aim Long Covid is often stigmatised, particularly in people who are disadvantaged within society. This may prevent them from seeking help and could lead to widening health inequalities. This coproduced study with a Community Advisory Board
Donna Clutterbuck, Mel Ramasawmy, Marija Pantelic, Jasmine Hayer, Fauzia Begum, Mark Faghy, Nayab Nasir, Barry Causer, Melissa Heightman, Gail Allsopp, Dan Wootton, M. Asad Khan, Claire Hastie, Monique Jackson, Clare Rayner, Darren Brown, Emily Parrett, Geraint Jones, Rowan Clarke, Sammie Mcfarland, Mark Gabbay, Amitava Banerjee, Nisreen A. Alwan, The STIMULATE‐ICP Consortium   +23 more
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

The potential bidirectional relationship between long COVID and menstruation [PDF]

Women have reported menstrual changes following SARS-CoV-2 infection and variation in long COVID symptoms across the menstrual cycle. We examined (i) whether COVID is linked to abnormal uterine bleeding (AUB), (ii) if long COVID symptoms vary with the ...
Alvergne, Alexandra, Critchley, Hilary O. D., Gibson, Douglas A., Homer, Natalie ZM., Jeanjean, Luna, Kountourides, Gabriella, Maybin, Jacqueline A., Olszewska, Zuzanna, Robb, Cara, Simpson, Joanna P., Walker, Catherine, Watters, Marianne   +11 more
core   +3 more sources

Muscle abnormalities worsen after post-exertional malaise in long COVID

Nature Communications
A subgroup of patients infected with SARS-CoV-2 remain symptomatic over three months after infection. A distinctive symptom of patients with long COVID is post-exertional malaise, which is associated with a worsening of fatigue- and pain-related symptoms
B. Appelman, B. Charlton, Richie P. Goulding, T. J. Kerkhoff, E. A. Breedveld, W. Noort, C. Offringa, F. Bloemers, M. van Weeghel, B. Schomakers, P. Coelho, J. Posthuma, E. Aronica, W. Joost Wiersinga, M. van Vugt, R. C. Wüst   +15 more
semanticscholar   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source