Results 141 to 150 of about 11,289,407 (322)

Co-creating a social science research agenda for Long Covid

Frontiers in Public Health
IntroductionOur objective was to understand how social scientific research could best address the needs and concerns of patients, families, carers, healthcare professionals, academics, private and public sector professionals, and volunteers from Long ...
Oonagh Cousins, Maaret Jokela-Pansini, Maaret Jokela-Pansini, Nisreen A. Alwan, Nisreen A. Alwan, Ella Barnard, Jo Dainow, Caroline Dalton, Gail Davies, Mark A. Faghy, Eileen Gilmour, Ian Patel, Ondine Sherwood, Lotus Westerhof, Beth Greenhough   +14 more
doaj   +1 more source

Solving the puzzle of Long Covid

Science
Long Covid provides an opportunity to understand how acute infections cause chronic disease More than 4 years into the global COVID-19 pandemic, widespread infection with severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) has left millions of ...
Z. Al-Aly, E. Topol
semanticscholar   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

MyGuide long COVID: An online self-management tool for people with long COVID

Internet Interventions
Background: Long COVID is a relatively new condition for which patients are asked to employ self-management strategies to manage their symptoms.
Hiten Naik, Kyla Pongratz, Michelle Malbeuf, Sonya Kung, Lori Last, Asuka Sugiyama, Esther Khor, Marlee McGuire, Adeera Levin, Karen C. Tran   +9 more
doaj   +1 more source

The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China.

Lancet. Infectious Diseases (Print)
BACKGROUND Growing evidence suggests that symptoms associated with post-COVID-19 condition (also known as long COVID) can affect multiple organs and systems in the human body, but their association with viral persistence is not clear.
Wenting Zuo, Di He, Chaoyang Liang, Shiyu Du, Zhan Hua, Qiangqiang Nie, Xiaofeng Zhou, Meng Yang, H. Tan, Jiuyang Xu, Yanbing Yu, Y. Zhan, Ying Zhang, Xiaoying Gu, Weijie Zhu, Hui Zhang, Hongyan Li, Weiliang Sun, Mingzhi Sun, Xiaolei Liu, Liguo Liu, Chuanzhen Cao, Rui Li, Jing Li, Yun Zhang, Yuting Zhang, Jing Guo, Ling Zhao, Chuan-Peng Zhang, Hongyu Liu, Shiyao Wang, Fei Xiao, Ye-ming Wang, Zai Wang, Haibo Li, B. Cao   +35 more
semanticscholar   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Long COVID and Health Inequalities: What's Next for Research and Policy Advocacy?

Health Expectations
Introduction Organised by the ‘Qualitative Long Covid Network’, a workshop for qualitative Long COVID (LC) researchers, LC charity representatives and people with LC took place in June 2023, where research on the intersectional inequalities affecting LC ...
Sarah Akhtar Baz, Mirembe Woodrow, Donna Clutterbuck, Chao Fang, Jordan Mullard, Amitava Banerjee, Sarah Barley‐McMullen, Jd Carpentieri, Anne‐Laure Donskoy, Alice Faux‐Nightingale, Sasha Lewis‐Jackson, Margaret E. O'Hara, Tanvi Rai, Ondine Sherwood, Nina Smyth, Kirsty Stanley, Victoria Welsh, Ghazala Mir, Nisreen A. Alwan   +18 more
doaj   +1 more source

Who Is the Intermediate Host of RNA Viruses? A Study Focusing on SARS-CoV-2 and Poliovirus

Microorganisms
The COVID-19 pandemic has sparked a surge in research on microbiology and virology, shedding light on overlooked aspects such as the infection of bacteria by RNA virions in the animal microbiome.
Carlo Brogna, Domenico Rocco Bisaccia, Vincenzo Costanzo, Gennaro Lettieri, Luigi Montano, Valentina Viduto, Mark Fabrowski, Simone Cristoni, Marina Prisco, Marina Piscopo   +9 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Assembling a True “Olympic Gel” From over 16 000 Combinatorial DNA Rings

Advanced Materials, EarlyView.
Olympic gels are an elusive class of soft matter, consisting of molecular networks held together purely by mechanically interlocked rings. Their topological structure promises unique properties and functions, but their synthesis has proven notoriously difficult.
Sarah K. Speed, Yu‐Hsuan Peng, Azra Atabay, Krishna Gupta, Toni Müller, Carolin Fischer, Ilka M. Hermes, Jens‐Uwe Sommer, Michael Lang, Elisha Krieg   +9 more
wiley   +1 more source