Results 161 to 170 of about 16,768,241 (334)

Dancing Through Long Covid: An Innovative Tale of Public Engagement [PDF]

In the realm of public engagement and the pursuit of inclusivity, the poster was an immersive experience for attendees: a journey where the power of dance converged with the clinicla research in 'Long Covid Diaries.' Through this poster, the objective ...
Marshall, A.
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Practical Recommendations for Exercise Training in Patients with Long COVID with or without Post-exertional Malaise: A Best Practice Proposal

Sports Medicine - Open
People with long COVID may suffer from a wide range of ongoing symptoms including fatigue, exertional dyspnea, reduced exercise performance, and others.
R. Gloeckl, Ralf H. Zwick, U. Fürlinger, T. Schneeberger, D. Leitl, I. Jarosch, U. Behrends, C. Scheibenbogen, A. R. Koczulla   +8 more
semanticscholar   +1 more source

Anti-interferon α-antibodies in pediatric patients with COVID-19 and long COVID

Introduction The involvement of neutralizing antibodies against type I interferon (IFN-I) in the development of severe coronavirus disease 2019 (COVID-19) in adult patients has been well documented.
Tetiana Kosovska, Oksana Boyarchuk, Vita Perestiuk, Liubov Volianska   +3 more
core   +1 more source

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

Reporting of pre-existing multiple long-term conditions in physical rehabilitation for long COVID: a scoping review

European Respiratory Review
Background Physical rehabilitation may improve health and wellbeing outcomes for some adults living with long COVID. However, individuals living with pre-existing multiple long-term conditions (MLTCs) and long COVID may have additional rehabilitation ...
Lucy Gardiner, Hannah M.L. Young, Holly Drover, Emily Morgan-Selvaratnam, Michael Natt, Nikki Smith, Enya Daynes, Mark W. Orme, Rod S. Taylor, Sally J. Singh, Rachael A. Evans   +10 more
doaj   +1 more source

Long COVID Frailty: A Comparative Analysis in a Veteran Population

Long COVID is characterized by persistent symptoms affecting one or more organ systems for at least 3 months following a SARS-CoV-2 infection. Our study aimed to examine the characteristics of frailty seen in patients with Long COVID compared to the ...
Jerry Bradley, Fei Tang, Natasha M. Resendes, Leonardo Tamariz, Tamariz, Leonardo, Palacio, Ana, Victor D. Cevallos, Hammel, Iriana S., Bradley, Jerry, Cevallos, Victor D., Dominique M. Tosi, Bast, Elizabeth, Elizabeth Bast, Iriana S. Hammel, Resendes, Natasha M., Tosi, Dominique M., Tang, Fei, Ana Palacio   +17 more
core   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

Advanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia, Shukui Zhang, Kai Ma, Jie Zhou, Jianwei Jiao   +4 more
wiley   +1 more source

Spontaneous, persistent, T cell–dependent IFN-γ release in patients who progress to Long Covid

Science Advances
After acute infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a proportion of patients experience persistent symptoms beyond 12 weeks, termed Long Covid.
Benjamin A Krishna, EY Lim, M. Metaxaki, Sarah Jackson, Lenette Mactavous, Paul A. Lyons, R. Doffinger, J. Bradley, Kenneth G. C. Smith, John Sinclair, Nicholas J. Matheson, Paul J. Lehner, Nyaradzai Sithole, M. Wills   +13 more
semanticscholar   +1 more source