Results 71 to 80 of about 519,655 (258)

The role of comorbidity in the development of Long-COVID

Клінічна та профілактична медицина, 2022
Introduction. Elimination of intracellular energy deficit and "smoldering" systemic inflammation, as well as elimination of water-electrolyte and metabolic disorders can be singled out as the main directions of therapy for the long-term consequences of ...
T.V. Chernii, V. I. Chernii, D. A. Fokina   +2 more
doaj   +1 more source

Long COVID: clues about causes

European Respiratory Journal, 2023
Many patients report persistent symptoms after resolution of acute COVID-19, regardless of SARS-CoV-2 variant and even if the initial illness is mild [1, 2]. A multitude of symptoms have been described under the umbrella term ‘Long COVID’, otherwise known as ‘post-COVID syndrome’ or ‘post-acute sequelae of SARS-CoV-2 (PASC)’; for simplicity we will use
Felicity Liew, Claudia Efstathiou, Peter J.M. Openshaw   +2 more
openaire   +2 more sources

Differences in Long COVID severity by duration of illness, symptom evolution, and vaccination: a longitudinal cohort study from the INSPIRE group [PDF]

BackgroundAlthough short-term outcomes of Long COVID have been described, longer-term physical and mental health outcomes of Long COVID are less well-established.
Chen, Ji, Dyal, Jonathan W, Elmore, Joann G, Gatling, Kristyn, Gentile, Nicole L, Geyer, Rachel E, Gottlieb, Michael, Hill, Mandy J, Kean, Efrat, L'Hommedieu, Michelle, Malicki, Caitlin, Montoy, Juan Carlos C, O'Laughlin, Kelli N, Rising, Kristin L, Rodriguez, Robert M, Santangelo, Michelle, Saydah, Sharon, Spatz, Erica S, Stephens, Kari A, Venkatesh, Arjun K, Wang, Ralph C, Weinstein, Robert A, Wisk, Lauren E, Yu, Huihui   +23 more
core   +1 more source

New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs, Willie J. Hale, Casey L. Straud, Jim Mintz, Stacey Young‐McCaughan, Kimberly D. Gomes, Chelsea J. Sterne, Katrina M. Lawrence‐Wolff, Alan J. Bartholomew, Kevin M. Kelly, Douglas M. Maurer, Catherine Vriend, Brett T. Litz, Douglas E. Williamson, Alan L. Peterson, for the STRONG STAR Consortium   +15 more
wiley   +1 more source

Patient characteristics associated with clinically coded long COVID: an OpenSAFELY study using electronic health records [PDF]

Background Clinically coded long COVID cases in electronic health records are incomplete, despite reports of rising cases of long COVID. Aim To determine patient characteristics associated with clinically coded long COVID.
Bacon, Sebastian, Cezard, Genevieve, Chaturvedi, Nish, Davy, Simon, Denaxas, Spiros, Denholm, Rachel, Fisher, Louis, Goldacre, Ben, Greaves, Felix, Horne, Elsie Mf, Knight, Rochelle, Macleod, John, Mehrkar, Amir, Riley, Stephanie, Sheikh, Aziz, Silverwood, Richard J, Sterne, Jonathan, Steves, Claire, Taylor, Kurt, Walker, Alex J, Walker, Venexia, Wei, Yinghui, Willans, Robert, Williams, Dylan M, Wood, Angela M   +24 more
core   +2 more sources

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

The potential bidirectional relationship between long COVID and menstruation [PDF]

Women have reported menstrual changes following SARS-CoV-2 infection and variation in long COVID symptoms across the menstrual cycle. We examined (i) whether COVID is linked to abnormal uterine bleeding (AUB), (ii) if long COVID symptoms vary with the ...
Alvergne, Alexandra, Critchley, Hilary O. D., Gibson, Douglas A., Homer, Natalie ZM., Jeanjean, Luna, Kountourides, Gabriella, Maybin, Jacqueline A., Olszewska, Zuzanna, Robb, Cara, Simpson, Joanna P., Walker, Catherine, Watters, Marianne   +11 more
core   +3 more sources

Combinatorial Synthesis of Next Generation Water‐Soluble Quaternized N‐Halamine Oligomers with Long‐Lasting Antiviral Properties

Advanced Functional Materials, EarlyView.
A combinatorial library of dual‐functional antiviral oligomers incorporating N‐halamine and quaternary ammonium functionalities is developed for long‐lasting antiviral activity. The lead materials exhibit rapid and durable antiviral activity against SARS‐CoV‐2 variants and influenza H1N1, with 4 to 5 log reduction in viral copies at 5 mg mL−1 ...
Eid Nassar‐Marjiya, Konda Reddy Kunduru, Krishanu Ghosal, Luna Rizik, Nofar Atari, Mahran Daifa, Neta Kutner, Bassma Khamaisi, Qi Wu, Simran Jindal, Merna Shaheen‐Mualim, Ranabir Majumder, Mahitosh Mandal, Michal Mandelboim, Shady Farah   +14 more
wiley   +1 more source

Inactivating SARS‐CoV‐2 Virus with MOF‐Composites as Smart Face Masks

Advanced Functional Materials, EarlyView.
In situ preparation and functionalization of MOF@Cotton fabrics as smart face masks for the immobilization of proteins and inactivation viruses, such as SARS‐CoV‐2. Abstract The significant impact of the SARS‐CoV‐2 (COVID‐19) pandemic outbreak on people's lives has highlighted the urgent need for effective personal protective equipment.
Romy Ettlinger, Aamod V. Desai, Hau Lam Jody Cheong, Louise L. Major, Terry K. Smith, Aaron B. Naden, Jane Hilton, Catherine S. Adamson, A. Robert Armstrong, Russell E. Morris   +9 more
wiley   +1 more source

Long COVID Illness: Disparities in Understanding and Receipt of Care in Emergency Department Populations [PDF]

Study objectiveMost long coronavirus disease (long COVID) studies rely on traditional surveillance methods that miss underserved populations who use emergency departments (EDs) as their primary health care source. In medically underserved ED populations,
Arreguin, Mireya I, Chakraborty, Lauren, Chinnock, Brian, Conn, Christopher, Eckstrand, Svea, Eucker, Stephanie A, Gottlieb, Michael, Kumar, Vijaya Arun, Mesbah, Heba, Molina, Melanie, Morse, Dana, Nichol, Graham, Rafique, Zubaid, Reyes, Karen, Rising, Kristin L, Rodriguez, Robert M, Shughart, Lindsey, Welch, Robert D   +17 more
core   +1 more source