Results 101 to 110 of about 15,157,814 (297)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Looking Ahead in Extension Work in Wilkin County

, 1957
This archival publication may not reflect current scientific knowledge or recommendations. Current information available from the University of Minnesota Extension: https://www.extension.umn.edu.Wilkin County Extension Long Range Planning Committee ...
Wilkin County Extension Long Range Planning Committee
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Analysis of Multifractal Characteristics and Detrended Cross-Correlation of Conventional Logging Data Regarding Igneous Rocks

Fractal and Fractional
In the current context of the global energy landscape, China is facing a growing challenge in oil and gas exploration and development. It is difficult to evaluate the log data because of the lithological composition of igneous rocks, which displays an ...
Shiyao Wang, Dan Mou, Xinghua Qi, Zhuwen Wang   +3 more
doaj   +1 more source

Exact Expressions of Spin-Spin Correlation Functions of the Two-Dimensional Rectangular Ising Model on a Finite Lattice

Entropy, 2018
We employ the spinor analysis method to evaluate exact expressions of spin-spin correlation functions of the two-dimensional rectangular Ising model on a finite lattice, special process enables us to actually carry out the calculation process.
Tao Mei
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

A Novel Shape Guided Transformer Network for Instance Segmentation in Remote Sensing Images

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Instance segmentation performance in remote sensing images (RSIs) is significantly affected by two issues: how to extract accurate boundaries of objects from remote imaging through the dynamic atmosphere, and how to integrate the mutual information of ...
Dawen Yu, Shunping Ji
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Looking Ahead in Extension Work in Redwood County

, 1957
This archival publication may not reflect current scientific knowledge or recommendations. Current information available from the University of Minnesota Extension: https://www.extension.umn.edu.Redwood County Extension Long Range Planning Committee ...
Redwood County Extension Long Range Planning Committee
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