Results 111 to 120 of about 15,157,814 (297)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Looking Ahead in Extension Work in Wadena County
, 1958 This archival publication may not reflect current scientific knowledge or recommendations. Current information available from the University of Minnesota Extension: https://www.extension.umn.edu.Wadena County Extension Long Range Planning Committee ...
Wadena County Extension Long Range Planning Committee
core
, 2012 We present a physically motivated correlation functional belonging to the meta-generalized gradient approximation (meta-GGA) rung, which can be supplemented with long-range dispersion corrections without introducing double-counting of correlation ...
Chałasiński, Grzegorz +4 more
core +1 more source
工程科学与技术, 2016 :In order to detect the dynamic mechanism of dry/wet changes and drought/flood prediction theory in hilly area of central Sichuan, potential evaporation was calculated with Penman-Monteith model and humid index was constructed, based on daily ...
wangzhen, liangchuan
doaj
Long Range Correlated Percolation
, 2006 In this note we study the field theory of dynamic isotropic percolation (DIP) with quenched randomness that has long range correlations decaying as $r^{-a}$. We argue that the quasi static limit of this field theory describes the critical point of long range correlated percolation.
openaire +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Looking Ahead in Extension Work in Nobles County
, 1957 This archival publication may not reflect current scientific knowledge or recommendations. Current information available from the University of Minnesota Extension: https://www.extension.umn.edu.Nobles County Extension Long Range Planning Committee ...
Nobles County Extension Long Range Planning Committee
core
, 2005 International audienceLong-range exchange and correlation effects, responsible for the failure of currently used approximate density functionals in describing van derWaals forces, are taken into account explicitly after a separation of the electron ...
Gerber, I.C. +6 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source