Results 121 to 130 of about 7,939,670 (409)
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
Background In 2009, the Dutch Health Care Inspectorate (IGZ) observed several serious risks to safety involving medication within elderly care facilities. However, by 2011, high risks had been reduced in almost all the organisations we visited.
J. A. Vermeulen+3 more
doaj +1 more source
Measuring social protection for long-term care
This report presents the first international quantification and comparison of levels of social protection for long-term care (LTC) in 14 OECD and EU countries.
T. Muir
semanticscholar +1 more source
Each year the South Carolina Long Term Care Ombudsman Program produced an annual report with a brief history, purpose of the program, quick facts and directory of programs with telephone ...
South Carolina Long Term Care Ombudsman Program
core
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Long-term care of patients with neurological disorders. [PDF]
Mark Wilkinson
openalex +1 more source
Long-Term-Care Utility and Late-in-Life Saving
Older wealth holders spend down assets much more slowly than predicted by classic life-cycle models. This paper introduces health-dependent utility into a model with incomplete markets in which preferences for bequests, expenditures when in need of long ...
J. Ameriks+4 more
semanticscholar +1 more source
Each year the South Carolina Long Term Care Ombudsman Program produced an annual report with a brief history, purpose of the program, quick facts and directory of programs with telephone ...
South Carolina Long Term Care Ombudsman Program
core
Long-term condition management in adults with intellectual disability in primary care: a systematic review [PDF]
Background: Adults with intellectual disabilities have higher morbidity and earlier mortality than the general population. Access to primary health care is lower, despite a higher prevalence of many long-term conditions.
Allan, Linda+4 more
core +1 more source