Results 101 to 110 of about 5,359,748 (310)

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Changing Economic Incentives in Long-Term Care [PDF]

open access: yes
Just as managed care has changed utilization and incentives in other parts of health care, there is a whole set of incentives built around long-term care that really matter.
R. Tamara Konetzka
core  

In Pursuit of Long-Term Care: Ensuring Access, Coverage, Quality [PDF]

open access: yes, 2002
Looks at the current and future demand for long-term supportive, medical, personal, and social services for an aging baby boomer population.
Janet Kline, Juliette Cubanski
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Study of predictors of mortality among older residents with pneumonia in Qatar's long-term care facilities

open access: yesAging and Health Research
It is widely recognized that older adults are at an increased risk of contracting pneumonia, which may lead to significant adverse outcomes, including increased rates of morbidity and mortality. The primary aim of this retrospective study was to identify
Shafi Hashmath Ulla Khan   +9 more
doaj   +1 more source

The German social long-term care insurance - structure and reform options [PDF]

open access: yes
Regarding social needs in Germany long-term care is an important issue due to an ageing population. Shrinking social networks are leading to a greater need for a public long-term care system.
Arntz, Melanie   +4 more
core  

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Long-Term Care Choices [PDF]

open access: yes, 2015
Consumers today have many choices when it comes to considering long-term care – whether they wish to remain in their home or community or move into an assisted living program or nursing home.

core  

Checkpoint blockade and the stem‐like T cell trade‐off

open access: yesMolecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Predictors of Actual Turnover Among Part‐Time Homecare Nurses in Japan: A Longitudinal Study

open access: yesJournal of General and Family Medicine
Background High turnover among homecare nurses leads to nursing shortages and a decline in care quality. In Japan, part‐time nurses are crucial to the workforce.
Maiko Noguchi‐Watanabe   +3 more
doaj   +1 more source

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