Results 91 to 100 of about 17,101,780 (300)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Long Term Care Ombudsman Annual Report, 1991-1992
, 1992 October 1, 1991 through March 31 ...
Kansas. Long Term Care Ombudsman
core +1 more source
BMC Health Services ResearchBackground Care problems such as decubitus and fall incidents are prevalent in nursing homes. Yet, research regarding explanatory factors on these care problems is scarce.
Suleyman Bouchmal +4 more
doaj +1 more source
Challenges of conducting research in long-term care facilities: a systematic review
BMC Geriatrics, 2018 BackgroundThe aim of this review is to describe the challenges and barriers to conducting research in long-term care facilities.MethodsA literature search was conducted in Ovid MEDLINE, Embase, Cochrane Central, PsycINFO and CINAHL.
Helen R. Lam +7 more
semanticscholar +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Values of Integrated Care: A Systematic Review
International Journal of Integrated Care, 2018 Introduction: Although substantial generic knowledge about integrated care has been developed, better understanding of the factors that drive behaviour, decision-making, collaboration and governance processes in integrated care networks is needed to take
Nick Zonneveld +3 more
doaj +1 more source
Global Convergence: Aging and Long-Term Care Policy Challenges in the Developing World
Journal of Aging & Social Policy, 2019 Aging around the world poses a global challenge in eldercare. This challenge is particularly felt in low- and middle-income countries (LMICs), where population aging outpaces the development of aged care policies and services. This Perspective highlights
Zhanlian Feng
semanticscholar +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
HeliyonBackground: Pelvic floor symptoms (PFS) are common and frequently co-occur, but few patients seek help despite negative effects on their quality of life. Moreover, most studies assessing help-seeking behaviour have only focused on a single PFS.
Kim Groot Wesseldijk +4 more
doaj +1 more source