Results 81 to 90 of about 17,101,780 (300)
Supplemental Digital Content is available in the text. Background: After critical illness, new or worsening impairments in physical, cognitive, and/or mental health function are common among patients who have survived.
M. Mikkelsen +31 more
semanticscholar +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
BackgroundStudies conducted on Western populations have shown that the Clinical Frailty Scale (CFS) is a major predictor of adverse outcomes in older patients with hip fractures; however, there are no data on Middle Eastern populations, who may be ...
Shirmila Syamala +6 more
doaj +1 more source
Trends and Challenges in Long-Term Care in Europe
The 21st century is a century of older people; the society is becoming long-lived. We are witnessing remarkable demographic changes; people are healthier, have higher quality of life and consequently live longer, which results in important social ...
Mateja Nagode, L. Lebar
semanticscholar +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Narrow Framing and Long‐Term Care Insurance
We propose a model of narrow framing in insurance and test it using data from a new module we designed and fielded in the Health and Retirement Study. We show that respondents subject to narrow framing are substantially less likely to buy long-term care ...
D. Gottlieb, Olivia S. Mitchell
semanticscholar +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Background Worldwide, the evidence-based 4Ms framework of the Age-Friendly Health System (AFHS) improves the experience of caring for older adults. This study aimed to examine healthcare professionals’ perceptions, attitudes, and behaviors regarding the ...
Hanadi Al Hamad +2 more
doaj +1 more source
Citizens as Active Participants in Integrated Care: Challenging the Field’s Dominant Paradigms
Policy makers, practitioners and academics often claim that care users and other citizens should be ‘at the center’ of care integration pursuits. Nonetheless, the field of integrated care tends to approach these constituents as passive recipients of ...
Ludo Glimmerveen, Henk Nies, Sierk Ybema
doaj +1 more source
Background: Care home staff stress and burnout may be related to high turnover and associated with poorer quality care. We systematically reviewed and meta-analyzed studies reporting stress and burnout and associated factors in staff for people living ...
H. Costello +3 more
semanticscholar +1 more source

