Results 111 to 120 of about 4,459,968 (325)

Restoration of Cingulate Long-Term Depression by Enhancing Non-apoptotic Caspase 3 Alleviates Peripheral Pain Hypersensitivity [PDF]

, 2020
Yongjie Wang, Ming‐Gang Liu, Jinghua Wang, Wei Cao, Cheng Wu, Ziyue Wang, Li Liu, Fan Yang, Zhihui Feng, Li Sun, Fu-Xing Zhang, Yi Shen, Yudong Zhou, Min Zhuo, Jianhong Luo, Tian‐Le Xu, Xiang‐Yao Li   +16 more
openalex   +1 more source

Depletion of Perineuronal Nets Enhances Recognition Memory and Long-Term Depression in the Perirhinal Cortex

Journal of Neuroscience, 2013
Perineuronal nets (PNNs) are extracellular matrix structures surrounding cortical neuronal cell bodies and proximal dendrites and are involved in the control of brain plasticity and the closure of critical periods.
C. Romberg, Sujeong Yang, Riccardo Melani, Melissa R. Andrews, Alexa E. Horner, M. Spillantini, T. Bussey, J. Fawcett, T. Pizzorusso, L. Saksida   +9 more
semanticscholar   +1 more source

The impact of positive lifestyle behaviors on direct healthcare cost savings for low back pain

Arthritis Care &Research, Accepted Article.
Objective This study aimed to investigate the relationship between a previously purpose‐developed lifestyle behavior scale and healthcare cost savings related to low back pain (LBP). Methods This longitudinal study utilised data from the AUstralian Twin BACK (AUTBACK) study. LBP and lifestyle behavior measures were collected at baseline.
Ye Tian, Katharine E. Roberts, Michelle Hall, Paula R. Beckenkamp, Angelo Sabag, Karoline Moe, Ana Paula Carvalho‐e‐Silva, Emily J. Callander, Paulo H. Ferreira   +8 more
wiley   +1 more source

Insulin induces long-term depression of VTA dopamine neurons via an endocannabinoid-mediated mechanism

Nature Neuroscience, 2013
The prevalence of obesity has markedly increased over the past few decades. Exploration of how hunger and satiety signals influence the reward system can help us understand non-homeostatic feeding.
G. Labouèbe, Shuai Liu, C. Dias, Haiyan Zou, Jovi C. Y. Wong, Subashini Karunakaran, S. M. Clee, A. Phillips, B. Boutrel, S. Borgland   +9 more
semanticscholar   +1 more source

Financial Distress and its Determinants in Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Objective To quantify the degree of financial distress and identify its determinants in adults with rheumatoid arthritis (RA) given the frequent chronic use of expensive disease modifying therapies. Methods We identified adults enrolled in the FORWARD databank with either RA or non‐inflammatory musculoskeletal disease (NIMSKD) completing the Functional
Amber Brown Keebler, Yunju Im, Sofia Pedro, Ted R. Mikuls, Edward S. Peters, Kaleb Michaud   +5 more
wiley   +1 more source

Long-term outcomes in patients with severe depression after in-hospital treatment – study protocol of the depression long-term Augsburg (DELTA) study

BMJ Open, 2019
Introduction Depressive disorders are very common diseases entailing a great burden on affected people. However, comprehensive information on long-term disease course in patients with severe depression is lacking so far. The objectives of the DELTA study
Jakob Linseisen, Inge Kirchberger, Barbara Maleckar, Christine Meisinger, Max Schmauss, Jessica Baumgärtner   +5 more
doaj   +1 more source

Exercise as treatment for depression [PDF]

, 2016
Studies have reported that physical activity can be protective against developing depression and that exercise can be as effective as pharmacotherapy or psychotherapy in the treatment of depression.
Helgadóttir, Björg
core   +1 more source

Testing A Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans

Arthritis Care &Research, Accepted Article.
Objective We aimed to test the efficacy of personalized treatment of older Veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABC) as compared with usual care (UC). Methods Two hundred ninety‐nine Veterans age 65‐89 with CLBP from 3 VA medical centers underwent baseline testing, randomization to ABC or UC and 12 months follow ...
Debra K. Weiner, Angela Gentili, Meika A. Fang, Edward Garay, Laura Lawson, Lenore Joseph, Cathy C. Lee, Michelle I. Rossi, Beverly Thorn, Subashan Perera   +9 more
wiley   +1 more source

Synaptic homeostasis transiently leverages Hebbian mechanisms for a multiphasic response to inactivity

Cell Reports
Summary: Homeostatic regulation of synapses is vital for nervous system function and key to understanding a range of neurological conditions. Synaptic homeostasis is proposed to operate over hours to counteract the destabilizing influence of long-term ...
Simón(e) D. Sun, Daniel Levenstein, Boxing Li, Nataniel Mandelberg, Nicolas Chenouard, Benjamin S. Suutari, Sandrine Sanchez, Guoling Tian, John Rinzel, György Buzsáki, Richard W. Tsien   +10 more
doaj   +1 more source

Sarm1 deficiency impairs synaptic function and leads to behavioral deficits, which can be ameliorated by an mGluR allosteric modulator

Frontiers in Cellular Neuroscience, 2014
Innate immune responses have been shown to influence brain development and function. Dysregulation of innate immunity is significantly associated with psychiatric disorders such as autism spectrum disorders (ASD) and schizophrenia, which are well-known ...
Chia-Wen eLin, Chiung-Ya eChen, Sin-Jhong eCheng, Hsiao-Tang eHu, Yi-Ping eHsueh   +4 more
doaj   +1 more source