Results 281 to 290 of about 4,590,611 (322)
Some of the next articles are maybe not open access.
Long-term management of depression
The American Journal of Medicine, 1994Major depression is often a chronic and recurrent disorder. Findings from a landmark study, the Pittsburgh Study of Maintenance Therapies in Recurrent Depression, demonstrate that full doses of antidepressants prevent recurrent depression and that maintenance therapy lasting at least 5 years may be required for patients with severely recurrent disease.
R M, Hirschfeld, A F, Schatzberg
openaire +2 more sources
Journal of the American Medical Directors Association, 2008
To review the diagnosis and treatment of depressive disorders in long-term care settings.A review of the literature on the diagnosis and treatment of depression in long-term care.Up to 35% of residents in long-term care facilities may experience either major depression or clinically significant depressive symptoms.
Mugdha, Thakur, Dan G, Blazer
openaire +2 more sources
To review the diagnosis and treatment of depressive disorders in long-term care settings.A review of the literature on the diagnosis and treatment of depression in long-term care.Up to 35% of residents in long-term care facilities may experience either major depression or clinically significant depressive symptoms.
Mugdha, Thakur, Dan G, Blazer
openaire +2 more sources
Long-term treatment of depression
European Neuropsychopharmacology, 1994In the late 1800's Kraepelin hypothesized that depression had a high probability for recovery. He described depression as acute episodes from which the patient returned to premorbid state of "well-being". It was postulated that there were subgroups who had a recurrent course, but the emphasis was on the theory that between episodes of depression ...
openaire +4 more sources
Long-Term Depression: Cerebellum
2001Long-term depression (LTD) displayed in the cerebellar cortex is a persistent decrease of the transmission efficacy from granule cell to Purkinje cells. LTD is induced when two inputs to a Purkinje cell, one from a climbing fiber and the other from a set of granule cell axons, are repeatedly associated.
openaire +1 more source
Depression: A Long-Term Illness
British Journal of Psychiatry, 1994The realisation that major depression is often both chronic and recurrent has slowly begun to change the way that depression is diagnosed and treated. In particular, the need for continuation and maintenance treatment is an issue that now deserves increased attention, especially with the availability of new classes of antidepressant treatments, which ...
openaire +2 more sources
Long-term Depression Overcomes Long-term Facilitation
Science Signaling, 2002In the short-term, a single neuron receiving multiple excitatory and inhibitory inputs at spatially distinct locales will sum all of them into the decision of whether or not to fire a nerve impulse. Guan et al. investigated the mechanisms whereby neurons integrate facilitatory and inhibitory inputs leading to long ...
openaire +2 more sources
Calcium signals in long-term potentiation and long-term depression
Canadian Journal of Physiology and Pharmacology, 1999We describe postsynaptic Ca2+signals that subserve induction of two forms of neuronal plasticity, long-term potentiation (LTP) and long-term depression (LTD), in rat hippocampal neurons. The common induction protocol for LTP, a 1-s, 50-Hz tetanus, generates Ca2+increases of about 50 µM in dendritic spines of CA1 neurons.
J A, Connor +3 more
openaire +2 more sources
Long-Term Potentiation, Long-Term Depression, and Learning
1998Publisher Summary Almost everyone agrees that information is acquired, stored, and retrieved by the brain. All brains consist of individual cellular elements. Most neurons have the same parts: a dendritic tree, cell body, axon, and synaptic boutons.
Joe L. Martinez +2 more
openaire +1 more source
Annales medico-psychologiques, 1990
Our practice, in a unit of treatment of dysthymic state being confronted with problems of relapses and recurrences, we have questioned the therapeutic strategies in the long run and their possible assessments. After recalling conceptual and methodological reference about relapses, recurrences and therapeutic assessment, we propose the methods and first
openaire +1 more source
Our practice, in a unit of treatment of dysthymic state being confronted with problems of relapses and recurrences, we have questioned the therapeutic strategies in the long run and their possible assessments. After recalling conceptual and methodological reference about relapses, recurrences and therapeutic assessment, we propose the methods and first
openaire +1 more source
Long-Term Potentiation and Long-Term Depression
2018Synaptic connections in the brain can change their strength in response to patterned activity. This ability of synapses is defined as synaptic plasticity. Long lasting forms of synaptic plasticity, long-term potentiation (LTP), and long-term depression (LTD), are thought to mediate the storage of information about stimuli or features of stimuli in a ...
openaire +1 more source