Results 21 to 30 of about 543,035 (258)
Motor cortical plasticity induced by motor learning through mental practice.
Frontiers in Behavioral Neuroscience, 2015 Several investigations suggest that actual and mental actions trigger similar neural substrates. Motor learning via physical practice results in long-term potentiation (LTP)-like plasticity processes, namely potentiation of M1 and a temporary occlusion ...
Laura eAvanzino +5 more
doaj +1 more source
The demise of the synapse as the locus of memory: A looming paradigm shift?
Frontiers in Systems Neuroscience, 2016 Synaptic plasticity is widely considered to be the neurobiological basis of learning and memory by neuroscientists and researchers in adjacent fields, though diverging opinions are increasingly being recognised. From the perspective of what we might call
Patrick C. Trettenbrein +1 more
doaj +1 more source
Long-Term Depression of a Dopamine IPSC [PDF]
The Journal of Neuroscience, 2007 Two determinants of dopamine release from terminals in striatal and limbic structures are the pattern and rate of dopamine neuron firing in the ventral midbrain. This activity is regulated in part by somatodendritic release of dopamine and subsequent feedback inhibition through activation of D2receptors on dopamine neuron cell bodies and dendrites ...
Michael J, Beckstead, John T, Williams
openaire +2 more sources
Peers, Gender, and Long-Term Depression [PDF]
SSRN Electronic Journal, 2020 We provide first evidence that peer depression in adolescence affects own depression in adulthood. We use data from Add Health and an identification strategy that relies on within-school and across-cohort idiosyncratic variation in the share of own-gender peers who are depressed. We find a significant peer effect for females but not for males.
Corrado Giulietti +2 more
openaire +6 more sources
A Practical Guide to Using CV Analysis for Determining the Locus of Synaptic Plasticity
Frontiers in Synaptic Neuroscience, 2020 Long-term synaptic plasticity is widely believed to underlie learning and memory in the brain. Whether plasticity is primarily expressed pre- or postsynaptically has been the subject of considerable debate for many decades. More recently, it is generally
Jennifer A. Brock +6 more
doaj +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Non-Hebbian Spike-Timing Dependent Plasticity in Cerebellar Circuits
Frontiers in Neural Circuits, 2013 Spike-timing dependent plasticity (STDP) provides a cellular implementation of the Hebb postulate, which states that synapses, whose activity repeatedly drives action potential firing in target cells, are potentiated.
Claire ePiochon +3 more
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2015 Estrogenic and androgenic steroids synthesized in the brain may rapidly modulate synaptic plasticity interacting with specific membrane receptors. We explored by electrophysiological recordings in hippocampal slices of male rat the influence of 17b ...
Michela eDi Mauro +6 more
doaj +1 more source
Predictors of long-term prognosis of depression [PDF]
Canadian Medical Association Journal, 2011 Many people with depression experience repeated episodes. Previous research into the predictors of chronic depression has focused primarily on the clinical features of the disease; however, little is known about the broader spectrum of sociodemographic and health factors inherent in its development.
Ian, Colman +5 more
openaire +2 more sources