Results 51 to 60 of about 8,108,857 (251)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Applied SciencesAiming to solve the challenges of the weak spatial and temporal correlation of medium- and long-term photovoltaic (PV) power data, as well as data redundancy and low forecasting efficiency brought about by long-time forecasting, this paper proposes a ...
Bin Wang +5 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
ECG Forecasting System Based on Long Short-Term Memory
BioengineeringWorldwide, cardiovascular diseases are some of the primary causes of death; yet the early detection and diagnosis of such diseases have the potential to save many lives.
Henriques Zacarias +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
IET Renewable Power GenerationWith the increasing penetration of grid‐scale wind energy systems, accurate wind power forecasting is critical to optimizing their integration into the power system, ensuring operational reliability, and enabling efficient system asset utilization ...
Mehmet Balci +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Long Term Care Ombudsman Annual Report, 1991-1992
, 1992 October 1, 1991 through March 31 ...
Kansas. Long Term Care Ombudsman
core +1 more source
United States Commission on Long-Term Care: Final Report to the Congress
, 2013 The federal Commission on Long-Term Care. Established as part of the American Taxpayer Relief Act of 2012 and signed into law January 2, 2013, the commission's goal was to advise Congress on how comprehensive, high-quality long-term care can be better ...
United States Senate Commission on Long-Term Care
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