Results 131 to 140 of about 1,220,900 (264)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Long-term Performance and Durability of Biomaterials and Implant Designs in Total Joint Arthroplasty and Spinal Fusion. [PDF]

J Orthop Sports Med
Parvizi D, Allahverdian A, Ayzenberg G, Kandikattu S, Sahafi R, Agrawal DK.   +5 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Return to Sport and Long-term Performance Levels in Weight Lifters Treated for Advanced Glenohumeral Arthritis With Inlay Total Shoulder Arthroplasty. [PDF]

Orthop J Sports Med
Barrett AA, Moutafis AD, Blashinsky ZA, Olsen DM, Ciesla CD, Torres-Caiaffa CA, Monem M, Schurhoff MR, Vargas LA, Zvijac JE, Uribe JW.   +10 more
europepmc   +1 more source

Long-Term Performance of Epicardial versus Transvenous Left Ventricular Leads for Cardiac Resynchronization Therapy. [PDF]

J Clin Med, 2023
de Maat GE, Mulder BA, Van de Lande ME, Rama RS, Rienstra M, Mariani MA, Maass AH, Klinkenberg TJ.   +7 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Long-term performance evaluation of a novel 3.26 GBq ⁶⁸Ge/⁶⁸Ga generator. [PDF]

EJNMMI Radiopharm Chem
Hu X, Hu R, Yang Y, Li Y, Zhao Y, Liu N, Ge Q, Zhang S, Ding S.   +8 more
europepmc   +1 more source

Ambiguous Role of Cations in the Long-Term Performance of Electrochemical Capacitors with Aqueous Electrolytes. [PDF]

ACS Appl Mater Interfaces, 2023
Platek-Mielczarek A, Piwek J, Frackowiak E, Fic K.   +3 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Long-Term Performance Evaluation of an FRP Composite Road Bridge Using DFOS Monitoring System. [PDF]

Sensors (Basel)
Kulpa M, Siwowski T, Rajchel M, Błazik-Borowa E, Jukowski M.   +4 more
europepmc   +1 more source