Results 11 to 20 of about 3,183,091 (359)

Long-term potentiation and long-term depression: a clinical perspective [PDF]

Clinics, 2011
Long-term potentiation and long-term depression are enduring changes in synaptic strength, induced by specific patterns of synaptic activity, that have received much attention as cellular models of information storage in the central nervous system.
Timothy V.P. Bliss, Sam F. Cooke
doaj   +5 more sources

Loss of the actin regulator cyclase-associated protein 1 (CAP1) modestly affects dendritic spine remodeling during synaptic plasticity

European Journal of Cell Biology, 2023
Dendritic spines form the postsynaptic compartment of most excitatory synapses in the vertebrate brain. Morphological changes of dendritic spines contribute to major forms of synaptic plasticity such as long-term potentiation (LTP) or depression (LTD ...
Anika Heinze, Marco B. Rust
doaj   +1 more source

Long-term potentiation in isolated dendritic spines. [PDF]

PLoS ONE, 2009
BACKGROUND:In brain, N-methyl-D-aspartate (NMDA) receptor (NMDAR) activation can induce long-lasting changes in synaptic alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptor (AMPAR) levels.
Amadou T Corera, Guy Doucet, Edward A Fon   +2 more
doaj   +1 more source

Core-Shell Dual-Gate Nanowire Charge-Trap Memory for Synaptic Operations for Neuromorphic Applications

Nanomaterials, 2021
This work showcases the physical insights of a core-shell dual-gate (CSDG) nanowire transistor as an artificial synaptic device with short/long-term potentiation and long-term depression (LTD) operation.
Md. Hasan Raza Ansari, Udaya Mohanan Kannan, Seongjae Cho   +2 more
doaj   +1 more source

Nutritional deficit and Long Term Potentiation alterations

Journal of Biological Research, 2009
In the present work we examined the ability of prenatally malnourished offspring to produce and maintain long-term potentiation (LTP) of the perforant path/dentate granule cell synapse in freely moving rats at 15,30, and 90 days of age.
M. Petrosino, G. Pizzuti
doaj   +1 more source

Rapid Recovery From Cortical Blindness Caused by an Old Cerebral Infarction

Frontiers in Neurology, 2020
When the primary visual cortex (V1) is damaged, cortical blindness results. However, visual information obtained from the superior colliculus (SC) or direct thalamic afferents to higher visual cortices produces unconscious visual functions called ...
Katsuei Shibuki, Katsuei Shibuki, Ichiro Wakui, Takeo Fujimura, Masaru Tomikawa, Shin Hasegawa   +5 more
doaj   +1 more source

Long-Term Potentiation: One Kind or Many? [PDF]

, 2016
Do neurobiologists aim to discover natural kinds? I address this question in this chapter via a critical analysis of classification practices operative across the 43-year history of research on long-term potentiation (LTP).
A Dolphin, AM Watabe, B Alger, C Craver, C Craver, C Craver, C Craver, C Craver, C Craver, C Craver, C Stinson, D Hebb, E Harris, E Kandel, E Kandel, G Lynch, G Lynch, G Piccinini, J Bickle, J Bogen, J Lisman, J Sullivan, J Woodward, JD English, JD English, JD Sweatt, JD Sweatt, K Kendler, M Baudry, M Baudry, M Bennett, M Browning, P Anderson, P Machamer, R Douglas, R Malenka, R Malenka, R Malenka, R Nicoll, R Nicoll, S Deadwyler, T Bliss, T Bliss, T Dunwiddie, T Lomo, U Feest, U Staubli, W Bechtel, W Bechtel, W Bechtel, W Wimsatt   +50 more
core   +3 more sources

Purkinje cells translate subjective salience into readiness to act and choice performance

Cell Reports, 2021
Summary: The brain selectively allocates attention from a continuous stream of sensory input. This process is typically attributed to computations in distinct regions of the forebrain and midbrain.
Lorenzo Bina, Vincenzo Romano, Tycho M. Hoogland, Laurens W.J. Bosman, Chris I. De Zeeuw   +4 more
doaj   +1 more source

Differential sensitivity of three forms of hippocampal synaptic potentiation to depotentiation

Molecular Brain, 2019
Theta-burst stimulation (TBS) induces short-term potentiation (STP) plus two types of transcriptionally-independent forms of long-term potentiation (LTP), termed LTP1 and LTP2.
Pojeong Park, Thomas M. Sanderson, Zuner A. Bortolotto, John Georgiou, Min Zhuo, Bong-Kiun Kaang, Graham L. Collingridge   +6 more
doaj   +1 more source

LIM-Kinases in Synaptic Plasticity, Memory, and Brain Diseases

Cells, 2021
Learning and memory require structural and functional modifications of synaptic connections, and synaptic deficits are believed to underlie many brain disorders.
Youssif Ben Zablah, Haiwang Zhang, Radu Gugustea, Zhengping Jia   +3 more
doaj   +1 more source