Results 11 to 20 of about 81,804 (294)
Nutritional deficit and Long Term Potentiation alterations
Journal of Biological Research, 2009 In the present work we examined the ability of prenatally malnourished offspring to produce and maintain long-term potentiation (LTP) of the perforant path/dentate granule cell synapse in freely moving rats at 15,30, and 90 days of age.
M. Petrosino, G. Pizzuti
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LIM-Kinases in Synaptic Plasticity, Memory, and Brain Diseases
Cells, 2021 Learning and memory require structural and functional modifications of synaptic connections, and synaptic deficits are believed to underlie many brain disorders.
Youssif Ben Zablah +3 more
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Differential sensitivity of three forms of hippocampal synaptic potentiation to depotentiation
Molecular Brain, 2019 Theta-burst stimulation (TBS) induces short-term potentiation (STP) plus two types of transcriptionally-independent forms of long-term potentiation (LTP), termed LTP1 and LTP2.
Pojeong Park +6 more
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Molecular Brain, 2022 Cyclin-dependent kinase 5 (Cdk5) /p35 is involved in many developmental processes of the central nervous system. Cdk5/p35 is also implicated in synaptic plasticity, learning and memory.
Miyuki Takahashi +9 more
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Long-term potentiation in the Eocene [PDF]
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003 Abstract The first ten years of long-term potentiation (LTP) research are reviewed. Surprisingly, given the intensity of current interest, the discovery paper did not trigger a wave of follow-on experiments. Despite this, the initial work laid out what ultimately became standard questions and paradigms.
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Long-term potentiation and memory [PDF]
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003 Abstract The discovery of long-term potentiation (LTP) transformed research on the neurobiology of learning and memory. This did not happen overnight, but the discovery of an experimentally demonstrable phenomenon reflecting activity-driven neuronal and synaptic plasticity changed discussions about what might underlie learning from ...
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The discovery of long-term potentiation [PDF]
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003 Abstract This paper describes circumstances around the discovery of long-term potentiation (LTP). In 1966, I had just begun independent work for the degree of Dr medicinae (PhD) in Per Andersen’s laboratory in Oslo after an eighteen-month apprenticeship with him.
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Stochastic Induction of Long-Term Potentiation and Long-Term Depression [PDF]
Scientific Reports, 2016 AbstractLong-term depression (LTD) and long-term potentiation (LTP) of granule-Purkinje cell synapses are persistent synaptic alterations induced by high and low rises of the intracellular calcium ion concentration ([Ca2+]), respectively. The occurrence of LTD involves the activation of a positive feedback loop formed by protein kinase C, phospholipase
Fábio M. Simões-de-Souza +2 more
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Frontiers in Cellular Neuroscience, 2019 Neuroactive estrogenic and androgenic steroids influence synaptic transmission, finely modulating synaptic plasticity in several brain regions including the hippocampus.
Alessandro Tozzi +9 more
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A prelude to long-term potentiation [PDF]
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003 Abstract Searching for premonitory studies of hippocampal long-term potentiation (LTP), there is a paucity of data. While synaptic enhancement during repetitive activation was studied in several reports from many groups between 1955 and 1967, the reported after-effects were short, at the most lasting a few minutes.
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