Results 1 to 10 of about 7,840,632 (290)

Presynaptic long-term potentiation requires extracellular signal-regulated kinases in the anterior cingulate cortex

open access: yesMolecular Pain, 2020
Extracellular signal-regulated kinases are widely expressed protein kinases in neurons, which serve as important intracellular signaling molecules for central plasticity such as long-term potentiation.
Qi-Yu Chen   +6 more
doaj   +1 more source

Core-Shell Dual-Gate Nanowire Charge-Trap Memory for Synaptic Operations for Neuromorphic Applications

open access: yesNanomaterials, 2021
This work showcases the physical insights of a core-shell dual-gate (CSDG) nanowire transistor as an artificial synaptic device with short/long-term potentiation and long-term depression (LTD) operation.
Md. Hasan Raza Ansari   +2 more
doaj   +1 more source

Long-Term Potentiation and Memory [PDF]

open access: yesPhysiological Reviews, 2004
Lynch, MA. Long-Term Potentiation and Memory. Physiol Rev 84: 87–136, 2004; 10.1152/physrev.00014.2003.—One of the most significant challenges in neuroscience is to identify the cellular and molecular processes that underlie learning and memory formation. The past decade has seen remarkable progress in understanding changes that accompany certain forms
Lynch, M. A., Ma, Lynch
openaire   +2 more sources

Nutritional deficit and Long Term Potentiation alterations

open access: yesJournal of Biological Research, 2009
In the present work we examined the ability of prenatally malnourished offspring to produce and maintain long-term potentiation (LTP) of the perforant path/dentate granule cell synapse in freely moving rats at 15,30, and 90 days of age.
M. Petrosino, G. Pizzuti
doaj   +1 more source

Geniposide attenuates postischemic long-term potentiation via GluN2A

open access: yesPakistan Journal of Pharmaceutical Sciences, 2021
N-Methyl-D-aspartate receptor (NMDAR)-induced antioxidation is a significant cause of neuronal injury after ischemic stroke. In a previous work, we verified the neuroprotective roles of geniposide during tMCAO in vivo. However, it remains unknown whether
Hua Yao   +10 more
doaj   +1 more source

Synaptic tagging and capture : differential role of distinct calcium/calmodulin kinases in protein synthesis-dependent long-term potentiation [PDF]

open access: yes, 2010
Weakly tetanized synapses in area CA1 of the hippocampus that ordinarily display long-term potentiation lasting ~3 h (called early-LTP) will maintain a longer-lasting change in efficacy (late-LTP) if the weak tetanization occurs shortly before or after ...
Okuno, Hiroyuki   +7 more
core   +1 more source

Long-term potentiation in the Eocene [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003
Abstract The first ten years of long-term potentiation (LTP) research are reviewed. Surprisingly, given the intensity of current interest, the discovery paper did not trigger a wave of follow-on experiments. Despite this, the initial work laid out what ultimately became standard questions and paradigms.
openaire   +2 more sources

Rapid Recovery From Cortical Blindness Caused by an Old Cerebral Infarction

open access: yesFrontiers in Neurology, 2020
When the primary visual cortex (V1) is damaged, cortical blindness results. However, visual information obtained from the superior colliculus (SC) or direct thalamic afferents to higher visual cortices produces unconscious visual functions called ...
Katsuei Shibuki   +5 more
doaj   +1 more source

Purkinje cells translate subjective salience into readiness to act and choice performance

open access: yesCell Reports, 2021
Summary: The brain selectively allocates attention from a continuous stream of sensory input. This process is typically attributed to computations in distinct regions of the forebrain and midbrain.
Lorenzo Bina   +4 more
doaj   +1 more source

Stochastic Induction of Long-Term Potentiation and Long-Term Depression [PDF]

open access: yesScientific Reports, 2016
AbstractLong-term depression (LTD) and long-term potentiation (LTP) of granule-Purkinje cell synapses are persistent synaptic alterations induced by high and low rises of the intracellular calcium ion concentration ([Ca2+]), respectively. The occurrence of LTD involves the activation of a positive feedback loop formed by protein kinase C, phospholipase
G. Antunes   +2 more
openaire   +2 more sources

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