Results 31 to 40 of about 8,199,342 (298)

Enhanced hippocampal long-term potentiation and spatial learning in aged 11ß-hydroxysteroid dehydrogenase type 1 knock-out mice [PDF]

open access: yes, 2007
Glucocorticoids are pivotal in the maintenance of memory and cognitive functions as well as other essential physiological processes including energy metabolism, stress responses, and cell proliferation.
Brownstein, D.   +29 more
core   +1 more source

Calcium-stimulated adenylyl cyclase subtype 1 is required for presynaptic long-term potentiation in the insular cortex of adult mice

open access: yesMolecular Pain, 2019
Recent studies indicate that presynaptic long-term potentiation in the anterior cingulate cortex may contribute to chronic pain-related anxiety. In addition to the anterior cingulate cortex, the insular cortex has also been indicated in chronic pain and ...
Hui-Hui Miao   +3 more
doaj   +1 more source

LIM-Kinases in Synaptic Plasticity, Memory, and Brain Diseases

open access: yesCells, 2021
Learning and memory require structural and functional modifications of synaptic connections, and synaptic deficits are believed to underlie many brain disorders.
Youssif Ben Zablah   +3 more
doaj   +1 more source

A prelude to long-term potentiation [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003
Abstract Searching for premonitory studies of hippocampal long-term potentiation (LTP), there is a paucity of data. While synaptic enhancement during repetitive activation was studied in several reports from many groups between 1955 and 1967, the reported after-effects were short, at the most lasting a few minutes.
openaire   +2 more sources

Long-Term Potentiation: The Accidental Discovery. [PDF]

open access: yesHippocampus
ABSTRACTLong‐term potentiation (LTP), is a type of synaptic plasticity now considered essential for learning and memory. Here I tell the story of how I accidentally discovered in 1966 in the laboratory of Per Andersen in Oslo, Norway, because I was not looking for it. It just emerged.
Lømo T.
europepmc   +3 more sources

The roles of STP and LTP in synaptic encoding [PDF]

open access: yesPeerJ, 2013
Long-term potentiation (LTP), a cellular model of learning and memory, is generally regarded as a unitary phenomenon that alters the strength of synaptic transmission by increasing the postsynaptic response to the release of a quantum of neurotransmitter.
Arturas Volianskis   +2 more
doaj   +2 more sources

Involvement of Cdk5 activating subunit p35 in synaptic plasticity in excitatory and inhibitory neurons

open access: yesMolecular Brain, 2022
Cyclin-dependent kinase 5 (Cdk5) /p35 is involved in many developmental processes of the central nervous system. Cdk5/p35 is also implicated in synaptic plasticity, learning and memory.
Miyuki Takahashi   +9 more
doaj   +1 more source

Melatonin inhibits hippocampal long-term potentiation [PDF]

open access: yes, 2012
The goal of this study is to investigate the effect of the hormone melatonin on long-term potentiation and excitability measured by stimulating the Schaffer collaterals and recording the field excitatory postsynaptic potential from the CA1 dendritic ...
Chaudhury, Dipesh   +4 more
core   +1 more source

Persistent memories of long-term potentiation and the -methyl-d-aspartate receptor

open access: yesBrain and Neuroscience Advances, 2019
In this article, we describe our involvement in the early days of research into long-term potentiation. We start with a description of the early experiments conducted in Oslo and London where long-term potentiation was first characterised. We discuss the
TVP Bliss, GL Collingridge
doaj   +1 more source

Bidirectional Synaptic Plasticity Is Driven by Sex Neurosteroids Targeting Estrogen and Androgen Receptors in Hippocampal CA1 Pyramidal Neurons

open access: yesFrontiers in Cellular Neuroscience, 2019
Neuroactive estrogenic and androgenic steroids influence synaptic transmission, finely modulating synaptic plasticity in several brain regions including the hippocampus.
Alessandro Tozzi   +9 more
doaj   +1 more source

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