Results 11 to 20 of about 80,675 (256)
Long-term potentiation and long-term depression: a clinical perspective [PDF]
Clinics, 2011 Long-term potentiation and long-term depression are enduring changes in synaptic strength, induced by specific patterns of synaptic activity, that have received much attention as cellular models of information storage in the central nervous system.
Timothy V.P. Bliss, Sam F. Cooke
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Long-Term Potentiation and Memory [PDF]
Physiological Reviews, 2004 Lynch, MA. Long-Term Potentiation and Memory. Physiol Rev 84: 87–136, 2004; 10.1152/physrev.00014.2003.—One of the most significant challenges in neuroscience is to identify the cellular and molecular processes that underlie learning and memory formation. The past decade has seen remarkable progress in understanding changes that accompany certain forms
Lynch, M. A., Ma, Lynch
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Long-term potentiation in the Eocene [PDF]
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003 Abstract The first ten years of long-term potentiation (LTP) research are reviewed. Surprisingly, given the intensity of current interest, the discovery paper did not trigger a wave of follow-on experiments. Despite this, the initial work laid out what ultimately became standard questions and paradigms.
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Stochastic Induction of Long-Term Potentiation and Long-Term Depression [PDF]
Scientific Reports, 2016 AbstractLong-term depression (LTD) and long-term potentiation (LTP) of granule-Purkinje cell synapses are persistent synaptic alterations induced by high and low rises of the intracellular calcium ion concentration ([Ca2+]), respectively. The occurrence of LTD involves the activation of a positive feedback loop formed by protein kinase C, phospholipase
G. Antunes +2 more
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Long-Term Potentiation: The Accidental Discovery. [PDF]
HippocampusABSTRACTLong‐term potentiation (LTP), is a type of synaptic plasticity now considered essential for learning and memory. Here I tell the story of how I accidentally discovered in 1966 in the laboratory of Per Andersen in Oslo, Norway, because I was not looking for it. It just emerged.
Lømo T.
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Pre-LTP requires extracellular signal-regulated kinase in the ACC
Molecular Pain, 2016 The extracellular signal-regulated kinase is an important protein kinase for cortical plasticity. Long-term potentiation in the anterior cingulate cortex is believed to play important roles in chronic pain, fear, and anxiety.
Manabu Yamanaka +3 more
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A prelude to long-term potentiation [PDF]
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003 Abstract Searching for premonitory studies of hippocampal long-term potentiation (LTP), there is a paucity of data. While synaptic enhancement during repetitive activation was studied in several reports from many groups between 1955 and 1967, the reported after-effects were short, at the most lasting a few minutes.
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Molecular Pain, 2019 Recent studies indicate that presynaptic long-term potentiation in the anterior cingulate cortex may contribute to chronic pain-related anxiety. In addition to the anterior cingulate cortex, the insular cortex has also been indicated in chronic pain and ...
Hui-Hui Miao +3 more
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Differential sensitivity of three forms of hippocampal synaptic potentiation to depotentiation
Molecular Brain, 2019 Theta-burst stimulation (TBS) induces short-term potentiation (STP) plus two types of transcriptionally-independent forms of long-term potentiation (LTP), termed LTP1 and LTP2.
Pojeong Park +6 more
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LIM-Kinases in Synaptic Plasticity, Memory, and Brain Diseases
Cells, 2021 Learning and memory require structural and functional modifications of synaptic connections, and synaptic deficits are believed to underlie many brain disorders.
Youssif Ben Zablah +3 more
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