Results 11 to 20 of about 8,199,342 (298)

Long-term potentiation and long-term depression: a clinical perspective [PDF]

Clinics, 2011
Long-term potentiation and long-term depression are enduring changes in synaptic strength, induced by specific patterns of synaptic activity, that have received much attention as cellular models of information storage in the central nervous system.
Timothy V.P. Bliss, Sam F. Cooke
doaj   +5 more sources

Discovery of a β-arrestin-biased CCKBR agonist that blocks CCKBR-dependent long-term potentiation [PDF]

Nature Communications
The CCKBR agonists induce neocortical long-term potentiation of excitatory synaptic transmission and enhance memory formation, while its antagonists weaken the potentiation in the amygdala and alleviate depression-like behaviors.
Heng Shi, Mengfan Zhang, Xiaofeng Hu, Jie Zhang, Tao Chen, Pingzhou Wu, Xue Wang, Shu Wei, George Choy, Stephen Temitayo Bello, Huifeng Chen, Chunhua Liu, Yiping Guo, Hongyan Sun, Jufang He   +14 more
doaj   +2 more sources

Long-Term Potentiation and Long-Term Depression

, 2018
Abstract Synaptic connections in the brain can change their strength in response to patterned activity. This ability of synapses is defined as synaptic plasticity. Long lasting forms of synaptic plasticity, long-term potentiation (LTP), and long-term depression (LTD), are thought to mediate the storage of information about stimuli or ...
Arianna Maffei
openaire   +2 more sources

Long-Term Potentiation

, 2013
Long-term potentiation was enhanced by nicotine exposure. Upper panel: Scattered plots of fEPSP against time revealed changes in fEPSP after long-term potentiation (LTP) induction by theta-burst stimulation.
Maria Antonietta Davoli (200426), Rosemary C. Bagot (322965), Tak Pan Wong (322983), Naguib Mechawar (143665), Claire-Dominique Walker (322975), Marissa Maheu (322978), Rachel F. Tyndale (322972), Ian Mahar (200421), Sheng-Hai Huang (322980), Sharon Miksys (322969)   +9 more
openaire   +2 more sources

Involvement of CX3CL1/CX3CR1 signaling in spinal long term potentiation. [PDF]

PLoS ONE, 2015
The long-term potentiation (LTP) of spinal C-fiber-evoked field potentials is considered as a fundamental mechanism of central sensitization in the spinal cord.
Chao Bian, Zhi-Qi Zhao, Yu-Qiu Zhang, Ning Lü   +3 more
doaj   +1 more source

Loss of the actin regulator cyclase-associated protein 1 (CAP1) modestly affects dendritic spine remodeling during synaptic plasticity

European Journal of Cell Biology, 2023
Dendritic spines form the postsynaptic compartment of most excitatory synapses in the vertebrate brain. Morphological changes of dendritic spines contribute to major forms of synaptic plasticity such as long-term potentiation (LTP) or depression (LTD ...
Anika Heinze, Marco B. Rust
doaj   +1 more source

Long-term potentiation in isolated dendritic spines. [PDF]

PLoS ONE, 2009
BACKGROUND:In brain, N-methyl-D-aspartate (NMDA) receptor (NMDAR) activation can induce long-lasting changes in synaptic alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptor (AMPAR) levels.
Amadou T Corera, Guy Doucet, Edward A Fon   +2 more
doaj   +1 more source

Presynaptic long-term potentiation requires extracellular signal-regulated kinases in the anterior cingulate cortex

Molecular Pain, 2020
Extracellular signal-regulated kinases are widely expressed protein kinases in neurons, which serve as important intracellular signaling molecules for central plasticity such as long-term potentiation.
Qi-Yu Chen, Zhi-Ling Zhang, Qin Liu, Chao-Jun Chen, Xiao-Kang Zhang, Ping-Yi Xu, Min Zhuo   +6 more
doaj   +1 more source

Core-Shell Dual-Gate Nanowire Charge-Trap Memory for Synaptic Operations for Neuromorphic Applications

Nanomaterials, 2021
This work showcases the physical insights of a core-shell dual-gate (CSDG) nanowire transistor as an artificial synaptic device with short/long-term potentiation and long-term depression (LTD) operation.
Md. Hasan Raza Ansari, Udaya Mohanan Kannan, Seongjae Cho   +2 more
doaj   +1 more source

Long-Term Potentiation and Memory [PDF]

Physiological Reviews, 2004
Lynch, MA. Long-Term Potentiation and Memory. Physiol Rev 84: 87–136, 2004; 10.1152/physrev.00014.2003.—One of the most significant challenges in neuroscience is to identify the cellular and molecular processes that underlie learning and memory formation. The past decade has seen remarkable progress in understanding changes that accompany certain forms
Lynch, M. A., Ma, Lynch
openaire   +2 more sources