Results 1 to 10 of about 119,810 (307)
Protein quality control of N-methyl-D-aspartate receptors
Frontiers in Cellular Neuroscience, 2022 N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated cation channels that mediate excitatory neurotransmission and are critical for synaptic development and plasticity in the mammalian central nervous system (CNS). Functional NMDARs typically form
Taylor M. Benske +2 more
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Roles of N-Methyl-D-Aspartate Receptors (NMDARs) in Epilepsy
Frontiers in Molecular Neuroscience, 2022 Epilepsy is one of the most common neurological disorders characterized by recurrent seizures. The mechanism of epilepsy remains unclear and previous studies suggest that N-methyl-D-aspartate receptors (NMDARs) play an important role in abnormal ...
Shuang Chen +5 more
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The Journal of Poultry Science, 2020 L-Pipecolic acid is an intermediate of L-lysine catabolism. Its central injection exerted a hypnotic effect on the brain, which was partially mediated by the activation of γ-aminobutyric acid-A and γ-aminobutyric acid-B receptors. L-Proline has also been
Asako Shigemura +2 more
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Frontiers in Psychiatry, 2023 BackgroundAntibodies against N-methyl-D-aspartate receptors are the most commonly identified cause of autoimmune encephalitis. While predominantly associated with malignancies, cases of anti-N-methyl-D-aspartate receptor autoimmune encephalitis have been
Thomas Hainmueller +4 more
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Philippine Journal of Obstetrics and Gynecology, 2021 A 24-year-old nulligravida who presented with seizures and behavioral changes with prodrome of flu-like symptoms was initially treated as a case of viral encephalitis.
Finella Marie G. Leonido +1 more
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Amiloride but not memantine reduces neurodegeneration, seizures and myoclonic jerks in rats with cardiac arrest-induced global cerebral hypoxia and reperfusion. [PDF]
PLoS ONE, 2013 It has been reported that both activation of N-methyl-D-aspartate receptors and acid-sensing ion channels during cerebral ischemic insult contributed to brain injury.
Kwok Keung Tai, Daniel D Truong
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Anti-N-methyl-D-aspartate Receptor Encephalitis [PDF]
Cureus, 2019 Anti-N-methyl-D-aspartate receptor (NMDA) encephalitis is an underrecognized encephalitis that may be mistaken for a wide variety of mental illnesses and causes of delirium. This syndrome is predominantly present in young females presenting with acute psychotic episodes, autonomic instability, and neurologic abnormalities.
Tanquary, Gregory +2 more
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NR2A- and NR2B-containing NMDA Receptors in the Prelimbic Medial Prefrontal Cortex Differentially Mediate Trace, Delay, and Contextual Fear Conditioning [PDF]
, 2013 Activation of N-methyl-D-aspartate receptors (NMDAR) in the prelimbic medial prefrontal cortex (PL mPFC) is necessary for the acquisition of both trace and contextual fear memories, but it is not known how specific NR2 subunits support each association ...
Gilmartin, Marieke R. +2 more
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Positive allosteric modulation as a potential therapeutic strategy in anti-NMDA receptor encephalitis [PDF]
, 2018 N-methyl-d-aspartate receptors (NMDARs) are ionotropic glutamate receptors important for synaptic plasticity, memory, and neuropsychiatric health. NMDAR hypofunction contributes to multiple disorders, including anti-NMDAR encephalitis (NMDARE), an ...
Benz, Ann +11 more
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Modulatory effects mediated by metabotropic glutamate receptor 5 on lateral geniculate nucleus relay cells [PDF]
, 2005 [Abstract] Glutamate is thought to be the excitatory neurotransmitter in the lateral geniculate nucleus (LGN) of the cat, mediating visual transmission from the retina via ionotropic receptors of both d,l-α-amino-3-hydroxy-5-α-methyl-4 ...
Cudeiro, Javier +2 more
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