The effects of AMPA receptor blockade on resting magnetoencephalography recordings [PDF]
, 2017 The ionotropic N-methyl-D-aspartate and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors of the glutamatergic neurotransmitter system are of fundamental importance to healthy brain function.
Khalid, Hamandi +3 more
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Role of N-methyl-D-aspartate receptors in action-based predictive coding deficits in schizophrenia [PDF]
, 2017 Published in final edited form as:Biol Psychiatry. 2017 March 15; 81(6): 514–524. doi:10.1016/j.biopsych.2016.06.019.BACKGROUND: Recent theoretical models of schizophrenia posit that dysfunction of the neural mechanisms subserving predictive coding ...
Ford, Judith M. +7 more
core +1 more source
N-Methyl-D-Aspartate Receptors in Hematopoietic Cells: What Have We Learned?
Frontiers in Physiology, 2020 The N-methyl-D-aspartate receptor (NMDAR) provides a pathway for glutamate-mediated inter-cellular communication, best known for its role in the brain but with multiple examples of functionality in non-neuronal cells.
Maggie L. Kalev-Zylinska +6 more
doaj +1 more source
An expanding range of targets for kynurenine metabolites of tryptophan [PDF]
, 2013 The kynurenine pathway of tryptophan metabolism accounts for most of the tryptophan that is not committed to protein synthesis and includes compounds active in the nervous and immune systems.
Darlington, L. Gail +2 more
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Anti-N-methyl-D-aspartate receptor encephalitis: analysis of three cases
Chinese Journal of Contemporary Neurology and Neurosurgery, 2018 Objective To explore the clinical features, diagnosis, treatment and prognosis of patients with anti-N-methyl-D-aspartate (NMDA) receptor encephalitis.
Ya-nan TIAN
doaj +1 more source
Cyclisation of Cell Penetrating PDZ-Binding Peptides Directed to PSD95 [PDF]
, 2019 Excitatory glutamatergic neurotransmission via N-methyl-D-aspartate receptor (NMDAR) is critical for synaptic plasticity and survival of neurons. Excessive NMDAR activity, however can cause excitotoxicity and promote cell death, underlying a potential ...
Al-Nasir, J +4 more
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Spatial and temporal boundaries of NMDA receptor hypofunction leading to schizophrenia
npj Schizophrenia, 2017 The N-methyl-d-aspartate receptor hypofunction is one of the most prevalent models of schizophrenia. For example, healthy subjects treated with uncompetitive N-methyl-d-aspartate receptor antagonists elicit positive, negative, and cognitive-like symptoms
Kazu Nakazawa +2 more
doaj +1 more source
Research progress of N⁃methyl⁃D⁃aspartate receptor GRIN2A gene variations and epilepsy
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 In recent years, with the rapid development of gene sequencing technology, a variety of epilepsy pathogenic genes have been discovered, among which GRIN2A gene variations encoding the neurotransmitter N⁃methyl⁃D⁃aspartate receptor (NMDAR) are closely ...
TANG Wei⁃ting, XIAO Bo
doaj +1 more source
In silico investigation on the probable macromolecular drug targets involved in the anti-schizophrenia activity of Nardostachys jatamansi [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2022 Existing medications i.e. the antipsychotic drugs are known to be effective in treating only the positive symptoms of schizophrenia, while being ineffective on negative and cognitive symptoms of the disease.
Foong Xi Wei +2 more
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Anti-N-Methyl-d-Aspartate Receptor Encephalitis
The American Journal of the Medical Sciences, 2013 A case of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis with an atypical finding of transient increased intracranial pressure is reported. Anti-NMDAR encephalitis is an underrecognized, novel and treatable form of encephalitis being increasingly identified as an explanation of encephalitis in young adults.
Sian Y, Lim +5 more
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