Results 1 to 10 of about 111,646 (306)
Roles of N-Methyl-D-Aspartate Receptors (NMDARs) in Epilepsy [PDF]
Frontiers in Molecular Neuroscience, 2022 Epilepsy is one of the most common neurological disorders characterized by recurrent seizures. The mechanism of epilepsy remains unclear and previous studies suggest that N-methyl-D-aspartate receptors (NMDARs) play an important role in abnormal ...
Shuang Chen +5 more
doaj +6 more sources
Long-term potentiation and the role of N -methyl- d -aspartate receptors
Brain Research, 2015 N-methyl-d-aspartate receptors (NMDARs) are known for their role in the induction of long-term potentiation (LTP). Here we start by reviewing the early evidence for their role in LTP at CA1 synapses in the hippocampus.
David Jane +2 more
exaly +3 more sources
Protein quality control of N-methyl-D-aspartate receptors [PDF]
Frontiers in Cellular Neuroscience, 2022 N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated cation channels that mediate excitatory neurotransmission and are critical for synaptic development and plasticity in the mammalian central nervous system (CNS). Functional NMDARs typically form
Taylor M. Benske +2 more
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The GluN3 subunit regulates ion selectivity within native N-methyl-d-aspartate receptors [PDF]
IBRO Reports, 2020 Glutamatergic N-methyl-d-aspartate receptors (NMDARs) are heterotetrameric proteins whose subunits are derived from three gene families, GRIN1 (codes for GluN1), GRIN2 (GluN2) and GRIN3 (GluN3).
Stephen Beesley +2 more
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N-Methyl-D-Aspartate Receptors in Hematopoietic Cells: What Have We Learned? [PDF]
Frontiers in Physiology, 2020 The N-methyl-D-aspartate receptor (NMDAR) provides a pathway for glutamate-mediated inter-cellular communication, best known for its role in the brain but with multiple examples of functionality in non-neuronal cells.
Maggie L. Kalev-Zylinska +6 more
doaj +2 more sources
Pharmacology of triheteromeric N-Methyl-D-Aspartate Receptors. [PDF]
Neurosci Lett, 2016 The N-Methyl-D-Aspartate Receptors (NMDARs) are heteromeric cation channels involved in learning, memory, and synaptic plasticity, and their dysregulation leads to various neurodegenerative disorders. Recent evidence has shown that apart from the GluN1/GluN2A and GluN1/GluN2B diheteromeric ion channels, the NMDAR also exists as a GluN1/GluN2A/GluN2B ...
Cheriyan J +3 more
europepmc +4 more sources
Advances and Barriers in Understanding Presynaptic N-Methyl-D-Aspartate Receptors in Spinal Pain Processing [PDF]
Frontiers in Molecular Neuroscience, 2022 For decades, N-methyl-D-aspartate (NMDA) receptors have been known to play a critical role in the modulation of both acute and chronic pain. Of particular interest are NMDA receptors expressed in the superficial dorsal horn (SDH) of the spinal cord ...
Annemarie Dedek +3 more
doaj +2 more sources
The Journal of Poultry Science, 2020 L-Pipecolic acid is an intermediate of L-lysine catabolism. Its central injection exerted a hypnotic effect on the brain, which was partially mediated by the activation of γ-aminobutyric acid-A and γ-aminobutyric acid-B receptors. L-Proline has also been
Asako Shigemura +2 more
doaj +1 more source
Frontiers in Psychiatry, 2023 BackgroundAntibodies against N-methyl-D-aspartate receptors are the most commonly identified cause of autoimmune encephalitis. While predominantly associated with malignancies, cases of anti-N-methyl-D-aspartate receptor autoimmune encephalitis have been
Thomas Hainmueller +4 more
doaj +1 more source
Philippine Journal of Obstetrics and Gynecology, 2021 A 24-year-old nulligravida who presented with seizures and behavioral changes with prodrome of flu-like symptoms was initially treated as a case of viral encephalitis.
Finella Marie G. Leonido +1 more
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