Results 21 to 30 of about 25,057,876 (282)
DEPRESSION-LIKE EFFECTS OF LEVETIRACETAM WAS HALTED BY PRETREATMENT WITH N-METHYL-D-ASPARTATE RECEPTOR (NMDAR) BLOCKERS IN MICE [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2023 N-methyl-D-aspartate receptor (NMDAR) stimulation might be responsible for levetiracetam -(Lev) induced depression. The aim of our study is to evaluate the effect of noncompetitive NMDAR blockers, dextromethorphan (Dxt) and dizocilpine (MK801), on Lev ...
Azadeh Mesripour, Tanin Ahmadi
doaj +1 more source
EPSPs in rat neocortical neurons in vitro. II. Involvement of N-methyl-D-aspartate receptors in the generation of EPSPs [PDF]
, 1989 1. Intracellular recordings were obtained from neurons in layer II/III of rat frontal cortex. Single-electrode current- and voltage-clamp techniques were employed to compare the sensitivity of excitatory postsynaptic potentials (EPSPs) and ...
J. J. Hablitz +3 more
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Anti-N-methyl-D-aspartate Receptor Encephalitis [PDF]
Cureus, 2019 Anti-N-methyl-D-aspartate receptor (NMDA) encephalitis is an underrecognized encephalitis that may be mistaken for a wide variety of mental illnesses and causes of delirium. This syndrome is predominantly present in young females presenting with acute psychotic episodes, autonomic instability, and neurologic abnormalities.
Tanquary, Gregory +2 more
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The effect of N-acetyl-aspartyl-glutamate and N-acetyl-aspartate on white matter oligodendrocytes [PDF]
, 2009 Elevations of the levels of N-acetyl-aspartyl-glutamate (NAAG) and N-acetyl-aspartate (NAA) are associated with myelin loss in the leucodystrophies Canavan's disease and Pelizaeus-Merzbacher-like disease. NAAG and NAA can activate and antagonize neuronal
Attwell, D. +9 more
core +1 more source
Pharmacology of triheteromeric N-Methyl-d-Aspartate Receptors [PDF]
Neuroscience Letters, 2016 The N-Methyl-D-Aspartate Receptors (NMDARs) are heteromeric cation channels involved in learning, memory, and synaptic plasticity, and their dysregulation leads to various neurodegenerative disorders. Recent evidence has shown that apart from the GluN1/GluN2A and GluN1/GluN2B diheteromeric ion channels, the NMDAR also exists as a GluN1/GluN2A/GluN2B ...
John, Cheriyan +3 more
openaire +2 more sources
, 1998 Protein kinase C modulation of N-methyl-D-Aspartate receptors: A role for exons and subunit ...
Stephen Millard. Logan (7971434)
core +6 more sources
Anti-N-methyl-D-aspartate receptor encephalitis: analysis of three cases
Chinese Journal of Contemporary Neurology and Neurosurgery, 2018 Objective To explore the clinical features, diagnosis, treatment and prognosis of patients with anti-N-methyl-D-aspartate (NMDA) receptor encephalitis.
Ya-nan TIAN
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N-Methyl-D-Aspartate Receptors in Hematopoietic Cells: What Have We Learned?
Frontiers in Physiology, 2020 The N-methyl-D-aspartate receptor (NMDAR) provides a pathway for glutamate-mediated inter-cellular communication, best known for its role in the brain but with multiple examples of functionality in non-neuronal cells.
Maggie L. Kalev-Zylinska +6 more
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Spatial and temporal boundaries of NMDA receptor hypofunction leading to schizophrenia
npj Schizophrenia, 2017 The N-methyl-d-aspartate receptor hypofunction is one of the most prevalent models of schizophrenia. For example, healthy subjects treated with uncompetitive N-methyl-d-aspartate receptor antagonists elicit positive, negative, and cognitive-like symptoms
Kazu Nakazawa +2 more
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Cardiac N-methyl d-aspartate Receptors as a Pharmacological Target [PDF]
Journal of Cardiovascular Pharmacology, 2016 Abstract: This study focuses on characterization of the cardiac N-methyl d-aspartate receptors (NMDARs) as a target for endogenous and synthetic agonists and antagonists. Using isolated perfused rat hearts, we have shown that intracoronary administration of the NMDAR agonists and antagonists has a pronounced effect on autonomous heart ...
Makhro, Asya +7 more
openaire +5 more sources