Results 91 to 100 of about 10,105,014 (311)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Long Term Care Ombudsman Annual Report, 2002

, 2003
October 1, 2002 to September 30 ...
Kansas. Long Term Care Ombudsman
core  

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

PREDIKSI TINGKAT CURAH HUJAN KOTA MATARAM MENGGUNAKAN LONG SHORT-TERM MEMORY

E-Jurnal Matematika
Rainfall is an important weather parameter that significantly influences the agricultural sector and regional planning. The City of Mataram, as the center of social and economic activities in West Nusa Tenggara Province, requires an accurate rainfall ...
DIMAS ANGGRAWAN HADINATA, IRENE RAINBOW KEWA SOMI, LULUK KARTIKA, TRI MARYONO RUSADI, SISKA APRILIA HARDIYANTI   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A novel solar radiation forecasting model based on time series imaging and bidirectional long short‐term memory network

Energy Science & Engineering
The instability of solar energy is the biggest challenge to its successful integration with modern power grids, and accurate prediction of long‐term solar radiation can effectively solve this problem.
Zhaoshuang He, Xue Zhang, Min Li, Shaoquan Wang, Gongwei Xiao   +4 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Prediction of long-term mortality.

, 2018
Prediction of long-term mortality.
K. Martijn Akkerhuis (817209), Eric Boersma (248258), Isabella Kardys (817218), Joost Daemen (5474747), Robert-Jan van Geuns (817217), Maxime M. Vroegindewey (5474741), Patrick W. Serruys (95423), Anne-Sophie Schuurman (5474744), Rohit M. Oemrawsingh (817213), Jurgen Ligthart (4429846)   +9 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source