Results 91 to 100 of about 11,529,759 (299)

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

What Can We Learn Four Years On? A Multi‐Centre Service Evaluation Exploring Symptoms, Functional Impact, Recovery and Care Pathways in Long Covid

Health Expectations
Background Long Covid (LC) is associated with long‐term health impacts that require ongoing support from healthcare services. We aimed to gain insights into patients' perceptions of their ongoing symptoms of LC, the effect on daily living and vocation ...
Cassie Lee, Paul Williams, Amiad Abrahams, Julie Darbyshire, Helen E. Davies, Johannes De Kock, Umut Esmer, Samantha A. Jones, Vicky Newey, Janet Scott, Nikki Smith, Darren Winch, Harsha Master, Sarah Elkin, LOCOMOTION Consortium   +14 more
doaj   +1 more source

Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment

Nature Neuroscience
Vascular disruption has been implicated in coronavirus disease 2019 (COVID-19) pathogenesis and may predispose to the neurological sequelae associated with long COVID, yet it is unclear how blood–brain barrier (BBB) function is affected in these ...
C. Greene, Ruairi Connolly, Declan Brennan, A. Laffan, Eoin O’Keeffe, Lilia Zaporojan, Jeffrey O’Callaghan, Bennett Thomson, Emma Connolly, Ruth Argue, James F. M. Meaney, I. Martín-Loeches, A. Long, C. N. Cheallaigh, N. Conlon, Colin P. Doherty, Matthew Campbell   +16 more
semanticscholar   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

The effectiveness of COVID-19 vaccines to prevent long COVID symptoms: staggered cohort study of data from the UK, Spain, and Estonia.

The Lancet Respiratory Medicine
BACKGROUND Although vaccines have proved effective to prevent severe COVID-19, their effect on preventing long-term symptoms is not yet fully understood.
M. Català, N. Mercadé-Besora, Raivo Kolde, N. T. Trinh, E. Roel, E. Burn, Trishna Rathod-Mistry, K. Kostka, W. Y. Man, A. Delmestri, H. Nordeng, A. Uusküla, T. Duarte-Salles, Daniel Prieto-Alhambra, A. Jödicke   +14 more
semanticscholar   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

The global prevalence of depression, anxiety, and sleep disorder among patients coping with Post COVID-19 syndrome (long COVID): a systematic review and meta-analysis

BMC Psychiatry
Post COVID-19 syndrome, also known as "Long COVID," is a complex and multifaceted condition that affects individuals who have recovered from SARS-CoV-2 infection.
N. Seighali, Abolfazl Abdollahi, Arman Shafiee, Mohammad Javad Amini, Mohammad Mobin Teymouri Athar, Omid Safari, Parsa Faghfouri, Alireza Eskandari, Omid Rostaii, A. Salehi, Hedieh Soltani, Mahsa Hosseini, Faeze Soltani Abhari, Mohammad Reza Maghsoudi, Bahar Jahanbakhshi, Mahmood Bakhtiyari   +15 more
semanticscholar   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Understanding the Clinical Characteristics and Timeliness of Diagnosis for Patients Diagnosed With Long Covid: A Retrospective Observational Cohort Study From North West London

Health Expectations
Background Long Covid is a multisystem condition first identified in the Covid‐19 pandemic, characterised by a wide range of symptoms including fatigue, breathlessness and cognitive impairment.
Denys Prociuk, Jonathan Clarke, Nikki Smith, Ruairidh Milne, Cassie Lee, Simon deLusignan, Ghazala Mir, Johannes De Kock, Erik Mayer, Brendan C. Delaney, LOCOMOTION Consortium   +10 more
doaj   +1 more source

Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches

GeroScience
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has introduced the medical community to the phenomenon of long COVID, a condition characterized by persistent symptoms following the resolution of the acute phase of infection.
T. Molnár, Andrea Lehoczki, M. Fekete, Reka Varnai, Laszlo Zavori, S. Erdő-Bonyár, Diána Simon, T. Berki, P. Csécsei, E. Ezer   +9 more
semanticscholar   +1 more source