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Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis
Arthritis Care &Research, EarlyView.Objective
We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods
We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.Timothy S. H. Kwok, Samantha Morais, William K. Silverstein, Clare L. Atzema, Gregory Choy, Priyanka Chandratre, Ping Li, Jessica Widdifield +7 morewiley +1 more sourceLarge-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease
Nature ImmunologyOne in ten severe acute respiratory syndrome coronavirus 2 infections result in prolonged symptoms termed long coronavirus disease (COVID), yet disease phenotypes and mechanisms are poorly understood1.F. Liew, C. Efstathiou, S. Fontanella, M. Richardson, R. Saunders, Dawid Swieboda, J. Sidhu, S. Ascough, S. Moore, N. Mohamed, J. Nunag, C. King, O. Leavy, O. Elneima, Hamish J C Mcauley, A. Shikotra, A. Singapuri, M. Sereno, V. Harris, L. Houchen-Wolloff, N. Greening, N. Lone, Matthew Thorpe, A. R. Thompson, S. Rowland-Jones, A. Docherty, J. Chalmers, Ling-Pei Ho, Alexander Horsley, B. Raman, K. Poinasamy, Michael Marks, Onn Min Kon, Luke S. Howard, D. Wootton, Jennifer Quint, T. D. de Silva, A. Ho, Christopher Chiu, Ewen M. Harrison, W. Greenhalf, J. Baillie, M. Semple, L. Turtle, Rachael A. Evans, L. Wain, C. Brightling, R. Thwaites, P. Openshaw, Kathryn H. Davies Oluwaseun Rita Laura Aguilar Shanaz N. A Abel Adamali Adeloye Adeyemi Adrego Jimenez Ahmad , Kathryn Abel, H. Adamali, D. Adeloye, O. Adeyemi, R. Adrego, L. Jimenez, Shanaz Ahmad, N. Haider, R. Ahmed, N. Ahwireng, M. Ainsworth, A. Alamoudi, Mariam Ali, M. Aljaroof, Louise M. Allan, R. Allen, L. Allerton, L. Allsop, Ann Marie Allt, P. Almeida, B. Al-Sheklly, D. Altmann, Maria Alvarez Corral, S. Amoils, D. Anderson, Charalambos Antoniades, G. Arbane, A. Arias, Cherie Armour, L. Armstrong, N. Armstrong, David Arnold, H. Arnold, A. Ashish, A. Ashworth, M. Ashworth, S. Aslani, H. Assefa-Kebede, P. Atkin, C. Atkin, R. Aul, H. Aung, L. Austin, C. Avram, Nikos Avramidis, A. Ayoub, M. Babores, R. Baggott, J. Bagshaw, D. Baguley, E. Bailey, J. Baillie, Steve Bain, M. Bakali, M. Bakau, E. Baldry, Molly M. Baldwin, D. Baldwin, C. Ballard, A. Banerjee, D. Bang, R. Barker, L. Barman, P. Barran, S. Barratt, F. Barrett, D. Basire, N. Basu, M. Bates, A. Bates, R. Batterham, H. Baxendale, G. Baxter, H. Bayes, M. Beadsworth, P. Beckett, M. Beggs, M. Begum, P. Beirne, M. Bell, Robert Bell, K. Bennett, E. Beranová, A. Bermperi, A. Berridge, C. Berry, S. Betts, E. Bevan, K. Bhui, M. Bingham, K. Birchall, L. Bishop, K. Bisnauthsing, J. Blaikely, A. Bloss, Annette Bolger, C. Bolton, J. Bonnington, A. Botkai, C. Bourne, M. Bourne, K. Bramham, L. Brear, G. Breen, J. Breeze, K. Breeze, A. Briggs, E. Bright, S. Brill, K. Brindle, L. Broad, A. Broadley, Claire Brookes, M. Broome, Vanessa Brown, M. Brown, Jo Brown, J. Brown, Ammani Brown, Angela Brown, M. Brown, Jeremy S Brown, Terry Brugha, Nigel J. Brunskill, M. Buch, P. Buckley, A. Bularga, E. Bullmore, J. Bunker, L. Burden, T. Burdett, D. Burn, G. Burns, A. Burns, J. Busby, R. Butcher, A. Butt, S. Byrne, P. Cairns, P. Calder, E. Calvelo, H. Carborn, B. Card, C. Carr, L. Carr, G. Carson, P. Carter, A. Casey, M. Cassar, Jonathon Cavanagh, M. Chablani, T. Chalder, James D. Chalmers, R. Chambers, F. Chan, K. Channon, K. Chapman, A. Charalambou, N. Chaudhuri, A. Checkley, Jin Chen, Yutung Cheng, L. Chetham, C. Childs, E. Chilvers, H. Chinoy, A. Chiribiri, K. Chong-James, N. Choudhury, G. Choudhury, P. Chowienczyk, C. Christie, M. Chrystal, C. Clark, D. Clark, J. Clarke, S. Clohisey, G. Coakley, Z. Coburn, S. Coetzee, Joby Cole, C. Coleman, F. Conneh, D. Connell, Bronwen Connolly, Lynda Connor, A. Cook, S. Cooper, B. Cooper, J. Cooper, D. Copeland, T. Cosier, E. Coughlan, M. Coulding, C. Coupland, E. Cox, T. Craig, P. Crisp, D. Cristiano, M. Crooks, A. Cross, I. Cruz, P. Cullinan, D. Cuthbertson, L. Daines, M. Dalton, P. Daly, A. Daniels, P. Dark, J. Dasgin, C. David, A. David, F. Davies, E. Davies, K. Davies, Gareth Davies, G. Davies, M. Davies, J. Dawson, Camilla Dawson, E. Daynes, A. Soyza, Bill Deakin, A. Deans, C. Deas, J. Deery, S. Defres, A. Dell, K. Dempsey, E. Denneny, J. Dennis, A. Dewar, R. Dharmagunawardena, N. Diar-Bakerly, C. Dickens, A. Dipper, S. Diver, S. Diwanji, M. Dixon, R. Djukanović, H. Dobson, S. Dobson, A. Docherty, A. Donaldson, T. Dong, N. Dormand, A. Dougherty, R. Dowling, S. Drain, K. Draxlbauer, K. Drury, P. Dulawan, A. Dunleavy, S. Dunn, C. Dupont, J. Earley, N. Easom, C. Echevarria, S. Edwards, C. Edwardson, A. Elliott, K. Elliott, Y. Ellis, A. Elmer, H. El-Taweel, T. Evans, R. Evans, D. Evans, R. Evans, H. Evans, J. Evans, C. Evenden, L. Evison, L. Fabbri, S. Fairbairn, A. Fairman, K. Fallon, D. Faluyi, C. Favager, T. Fayzan, J. Featherstone, T. Felton, V. Ferreira, J. Finch, S. Finney, J. Finnigan, L. Finnigan, H. Fisher, S. Fletcher, R. Flockton, M. Flynn, H. Foot, D. Foote, Amber Ford, D. Forton, E. Fraile, C. Francis, R. Francis, Susan Francis, A. Frankel, Emily A. Fraser, R. Free, N. French, X. Fu, Jonathon Fuld, J. Furniss, L. Garner, N. Gautam, J. Geddes, J. George, P. George, Michael Gibbons, R. Gill, M. Gill, L. Gilmour, F. Gleeson, J. Glossop, S. Glover, N. Goodman, C. Goodwin, B. Gooptu, H. Gordon, T. Gorsuch, M. Greatorex, P. Greenhaff, W. Greenhalf, A. Greenhalgh, J. Greenwood, R. Gregory, H. Gregory, D. Grieve, D. Griffin, L. Griffiths, A.-M. Guerdette, B. Guillen-Guio, M. Gummadi, Ayushman Gupta, S. Gurram, E. Guthrie, Z. Guy, K. Hadley, A. Haggar, K. Hainey, B. Hairsine, Pranab Haldar, L. Hall, I. Hall, M. Halling-Brown, R. Hamil, A. Hancock, K. Hancock, N. Hanley, Sulaimaan Haq, H. Hardwick, T. Hardy, E. Hardy, B. Hargadon, K. Harrington, E. Harris, Ewen M. Harrison, Paul J. Harrison, N. Hart, A. Harvey, M. Harvey, M. Harvie, L. Haslam, C. Hastie, M. Havinden-Williams, J. Hawkes, N. Hawkings, J. Haworth, A. Hayday, M. Haynes, J. Hazeldine, T. Hazelton, Liam G. Heaney, C. Heeley, J. Heeney, M. Heightman, S. Heller, M. Henderson, H. Henson, L. Hesselden, M. Hewitt, V. Highett, T. Hillman, T. Hiwot, L. Ho, M. Hoare, A. Hoare, J. Hockridge, P. Hogarth, A. Holbourn, S. Holden, L. Holdsworth, D. Holgate, M. Holland, L. Holloway, K. Holmes, M. Holmes, B. Holroyd-Hind, L. Holt, A. Hormis, Alexander Horsley, A. Hosseini, M. Hotopf, Luke S. Howard, K. Howard, A. Howell, E. Hufton, R. Hughes, J. Hughes, Alun Hughes, A. Humphries, N. Huneke, E. Hurditch, J. Hurst, Masud Husain, T. Hussell, J. Hutchinson, W. Ibrahim, F. Ilyas, J. Ingham, L. Ingram, D. Ionita, Karen Isaacs, K. Ismail, T. Jackson, J. Jacob, W. Y. James, W. Jang, C. Jarman, I. Jarrold, H. Jarvis, R. Jastrub, B. Jayaraman, Gisli Jenkins, P. Jezzard, K. Jiwa, C. Johnson, S. Johnson, D. Johnston, C. Jolley, S. Jones, H. Jones, L. Jones, Ian Jones, G. Jones, H. Jones, Mark G. Jones +499 moresemanticscholar +1 more sourceAutoimmunity in long COVID
Journal of Allergy and Clinical ImmunologyLong COVID (also termed postacute sequelae of SARS-CoV-2, or PASC) affects up to 10% of people recovering from infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Diagnosis is hampered by diffuse symptomatology, lack of biomarkers, incomplete understanding of pathogenesis, and lack of validated treatments.Shubha, Talwar, James A, Harker, Peter J M, Openshaw, Ryan S, Thwaites +3 moreopenaire +2 more sourcesAssociation of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis
Arthritis Care &Research, EarlyView.Objective
Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung +4 morewiley +1 more sourceLong COVID is associated with severe cognitive slowing: a multicentre cross-sectional study
EClinicalMedicineSummary Background COVID-19 survivors may experience a wide range of chronic cognitive symptoms for months or years as part of post-COVID-19 conditions (PCC). To date, there is no definitive objective cognitive marker for PCC.Sijia Zhao, Eva Maria Martin, P. Reuken, A. Scholcz, A. Ganse-Dumrath, Annie Srowig, I. Utech, Valeska Kozik, M. Radscheidt, Stefan Brodoehl, A. Stallmach, Matthias Schwab, Emily Fraser, K. Finke, Masud Husain +14 moresemanticscholar +1 more sourceTrajectories of persisting Covid- 19 symptoms up to 24 months after acute infection: findings from the Predi-Covid cohort study
BMC Infectious DiseasesIntroduction Long COVID is a multisystemic, fluctuating condition inducing a high burden on affected people. Despite the existence of some guidelines, its management remains complicated.Aurélie Fischer, Lu Zhang, Abir Elbéji, Paul Wilmes, Chantal J. Snoeck, Jérôme Larché, Pauline Oustric, Markus Ollert, Guy Fagherazzi +8 moredoaj +1 more source
