Results 111 to 120 of about 588,548 (249)

Long Non-Coding RNA and Breast Cancer [PDF]

Technology in Cancer Research & Treatment, 2019
Breast cancer, one of the most common diseases among women, is regarded as a heterogeneous and complicated disease that remains a major public health concern. Recently, owing to the development of next-generation sequencing technologies, long non-coding RNAs have received extensive attention.
Zhongxin Lu, Tangwei Wu, Hui Hu, Shuiyi Liu, Ge Yan, Ge Yan, Weiqun Chen, Yong Ning, Tianzhu Zhang, Tianzhu Zhang   +9 more
openaire   +3 more sources

Transcriptional and Post-transcriptional Gene Regulation by Long Non-coding RNA. [PDF]

, 2017
Advances in genomics technology over recent years have led to the surprising discovery that the genome is far more pervasively transcribed than was previously appreciated.
An, Andersson, Augoff, Bartel, Beermann, Broadbent, Cai, Calin, Carrieri, Chen, Chu, Cloonan, Costanza Emanueli, de Hoon, de Pontual, Diederichs, Djebali, Elton, Gabory, Gabory, Gao, Geisler, Gong, Gonzalez, Guttman, Hangauer, Hansen, Hansen, Hindorff, Iain M. Dykes, Imig, Ishii, Johnson, Johnsson, Kallen, Kampa, Kapranov, Kapranov, Kasar, Keniry, Khalil, Kim, Kim, Kim, Kino, Kretz, Krumlauf, Kumar, Lai, Lam, Lee, Leppek, Lerner, Li, Li, Li, Li, Luco, Malik, Mattick, Memczak, Mercer, Milligan, Monnier, Morenos, Mousavi, Nagano, Nagano, Novikova, Ong, Orom, Orom, Palazzo, Pandey, Papanayotou, Park, Pastori, Pegueroles, Poliseno, Rinn, Rinn, Rinn, Ripoche, Rutnam, Saini, Salmena, Salzman, Salzman, Sarma, Seitz, Siomi, Slezak-Prochazka, Smith, Somarowthu, Sotelo, Srisawat, St Laurent, Tam, Thomas, Thomson, Tripathi, Tsai, Underwood, Wan, Wang, Wang, Wang, Winter, Xiang, Yang, Yoon, Zemel, Zeng   +112 more
core   +4 more sources

Long intergenic non-coding RNA expression signature in human breast cancer [PDF]

, 2016
Breast cancer is a complex disease, characterized by gene deregulation. There is less systematic investigation of the capacity of long intergenic non-coding RNAs (lincRNAs) as biomarkers associated with breast cancer pathogenesis or several ...
Cai, Qiuyin, Guo, Xingyi, He, Chunyan, Long, Jirong, May, Isaac, Wagner, Erin K., Zhang, Yanfeng, Zheng, Wei   +7 more
core   +1 more source

Non-coding RNAs and glioblastoma: Insight into their roles in metastasis

Molecular Therapy: Oncolytics, 2022
Glioma, also known as glioblastoma multiforme (GBM), is the most prevalent and most lethal primary brain tumor in adults. Gliomas are highly invasive tumors with the highest death rate among all primary brain malignancies.
Seyed Mojtaba Mousavi, Maryam Derakhshan, Fatereh Baharloii, Fatemeh Dashti, Seyed Mohammad Ali Mirazimi, Maryam Mahjoubin-Tehran, Saereh Hosseindoost, Pouya Goleij, Neda Rahimian, Michael R. Hamblin, Hamed Mirzaei   +10 more
doaj  

EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks [PDF]

, 2019
The exosome is a ribonucleolytic complex that plays important roles in RNA metabolism. Here we show that the exosome is necessary for the repair of DNA double-strand breaks (DSBs) in human cells and that RNA clearance is an essential step in homologous ...
Bonath, Franziska, Domingo Prim, Judit, Endara Coll, Martin, Friedländer, Marc R., Huertas Sánchez, Pablo, Jimeno González, Sonia, Prados Carvajal, Rosario, Visa, Neus   +7 more
core   +2 more sources

Long non-coding RNA structure and function: Is there a link? [PDF]

, 2018
RNA has emerged as the prime target for diagnostics, therapeutics and the development of personalized medicine. In particular, the non-coding RNAs (ncRNAs) that do not encode proteins, display remarkable biochemical versatility.
Albrecht, Andreas A., Steinhofel, Kathleen, Zampetaki, Anna   +2 more
core   +6 more sources

Long non-coding RNAs in hematopoietic regulation

Cell Regeneration, 2018
Long non-coding RNAs (lncRNAs) have crucial roles via tethering with DNA, RNA or protein in diverse biological processes. These lncRNA-mediated interactions enhance gene regulatory networks and modulate a wide range of downstream genes. It has been demonstrated that several lncRNAs act as key regulators in hematopoiesis.
Yanmin Si, Jia Yu, Fang Wang, Yue Ren, Weiqian Li   +4 more
openaire   +3 more sources

Complete genome sequence of Alicyclobacillus acidocaldarius type strain (104-IA). [PDF]

, 2010
Alicyclobacillus acidocaldarius (Darland and Brock 1971) is the type species of the larger of the two genera in the bacillal family 'Alicyclobacillaceae'. A.
Brettin, Thomas, Bristow, Jim, Bruce, David, Chain, Patrick, Chang, Yun-Juan, Chen, Amy, Chen, Feng, Cheng, Jan-Fang, Chertkov, Olga, Copeland, Alex, Detter, John C, Eisen, Jonathan A, Glavina Del Rio, Tijana, Goodwin, Lynne, Göker, Markus, Han, Cliff, Hauser, Loren, Hugenholtz, Philip, Ivanova, Natalia, Jeffries, Cynthia D, Klenk, Hans-Peter, Kyrpides, Nikos C, Land, Miriam, Lapidus, Alla, Lucas, Susan, Markowitz, Victor, Mavromatis, Konstantinos, Meincke, Linda, Nolan, Matt, Ovchinnikova, Galina, Palaniappan, Krishna, Pati, Amrita, Pitluck, Sam, Pukall, Rüdiger, Rohde, Manfred, Sikorski, Johannes, Sims, David, Tice, Hope, Wahrenburg, Claudia   +38 more
core   +2 more sources

Review: Long non-coding RNA in livestock

Animal, 2020
Less than 2% of mammalian genomes code for proteins, but ‘the majority of its bases can be found in primary transcripts’ – a phenomenon termed the pervasive transcription, which was first reported in 2007.
B. Kosinska-Selbi, M. Mielczarek, J. Szyda   +2 more
doaj  

Into the Wild: GWAS Exploration of Non-coding RNAs [PDF]

, 2018
Genome-wide association studies (GWAS) have proven a fundamental tool to identify common variants associated to complex traits, thus contributing to unveil the genetic components of human disease.
Giral, Hector, Kratzer, Adelheid, Landmesser, Ulf   +2 more
core   +1 more source