Role of non-coding RNA in exosomes for the diagnosis and treatment of osteosarcoma
Frontiers in OncologyOsteosarcoma (OS) is a malignancy characterized by the proliferation of osteoblasts that predominantly affects pediatric and adolescent populations. At present, early detection of OS is significantly lacking, coupled with treatment challenges such as ...
Xin Liu +6 more
doaj +1 more source
Large-scale prediction of long non-coding RNA functions in a coding–non-coding gene co-expression network [PDF]
, 2011 Qi Liao +12 more
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The role of circular RNAs in regulating cytokine signaling in cancer
FEBS Open Bio, EarlyView.Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi +4 more
wiley +1 more source
Long non‐coding RNA MALAT1 regulates retinal neurodegeneration through CREB signaling
EMBO Molecular Medicine, 2022 Jin Yao +15 more
doaj +1 more source
Non-coding RNAs and exosomal non-coding RNAs in lung cancer: insights into their functions
Frontiers in Cell and Developmental BiologyLung cancer is the second most common form of cancer worldwide Research points to the pivotal role of non-coding RNAs (ncRNAs) in controlling and managing the pathology by controlling essential pathways. ncRNAs have all been identified as being either up-
Xiaolong Lv +3 more
doaj +1 more source
ncFANs: a web server for functional annotation of long non-coding RNAs [PDF]
, 2011 Qiang Liao +13 more
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Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
Non-coding RNAs as potential targets in metformin therapy for cancer
Cancer Cell InternationalMetformin, a widely used oral hypoglycemic drug, has emerged as a potential therapeutic agent for cancer treatment. While initially known for its role in managing diabetes, accumulating evidence suggests that metformin exhibits anticancer properties ...
Yihan Zhang +5 more
doaj +1 more source
Two long non-coding RNAs generated from subtelomeric regions accumulate in a novel perinuclear compartment in Plasmodium falciparum [PDF]
, 2012 Miguel Sierra-Miranda +7 more
openalex +1 more source